Week 1: Dyslipidemia Flashcards
What is the LDL threshold for automatic treatment? What is used to treat that level?
190
High-intensity statin
For patients with diabetes between 40-75, what needs to be added to their medication regimen?
moderate-intensity statin
consider high if ASCVD risk present
For patients between 20-39, when would you consider prescribing a statin?
family hx of premature ASCVD and LDL >160
For patients between 40-75 with LDL between 70-190 (no DM) and low risk ASCVD what is the plan?
lifestyle changes
For patients between 40-75 with LDL between 70-190 (no DM) and borderline risk ASCVD what is the plan?
Consider moderate intensity statin
For patients between 40-75 with LDL between 70-190 (no DM) and intermediate risk ASCVD what is the plan?
moderate-intensity statin
For patients between 40-75 with LDL between 70-190 (no DM) and high risk ASCVD what is the plan?
moderate-high intensity statin
Escalation plan - if a patient is on maximal statin therapy and LDL is >70, what would you do next?
Add ezetimibe
When is it reasonable to add the PCKS9 to the medication regimen?
if on maximal statin + Zetia and LDL >70 or non-HDL >100
What are the desirable lipid levels for a patient without diabetes?
LDL: 100
HDL: 60
TG: 150
TC: 200
What are the desirable lipid levels for a patient with diabetes?
LDL: 100
HDL 130
TG: 150
What combination is used to lower LDL?
statin, zetia, PCSK9
What combination is used to lower non-HDL, TG?
statin, omega-3 fatty acid, fibrate
What combination is used to lower LDL in familial hypercholesterolemia?
statin, PCSK9
Which statin can be used with CKD?
Atorvastatin
Which drug can lower A1C
Bile acid sequestrants
What is the high intensity vs. moderate intensity dosage for atorvastatin and rosuvastatin?
Atorvastatin: 40-80; 10-20
Rosuvastatin: 20-40; 5-10
