Week 1 - DNA structure Flashcards
A double stranded molecule found in each chromosome
deoxyribonucleic acid (DNA)
What sequence of nucleotide bases is attached in each chain of DNA?
Adenine, thymine, guanine, cytosine
How must the nucleotide bases be paired?
adenine to thymine, guanine to cytosine (the sequence determine genetic code)
Replication
in mitosis and other processes - the helix unravels and loose nucleotides are attracted to the unpaired strands and form two identical chromosomes (errors sometimes occur and result in mutations)
Structural genes
Contain info necessary for synthesis of proteins
Proteins
Long chains of amino acids that control physiological activities of cells and are important components of their structure
- All cells in body (e.g. brain, hair, bone etc.) contain exactly the same set of structural genes. How do cells develop differently?
Enhancer
Tell me about the role of an enhancer
- Sections of DNA that control structural genes and whether or not they initiate synthesis of protein
- If protein is synthesized the gene is expressed – no protein synthesis, gene is not expressed.
Again, what happens if the protein is not synthesized?
The gene is not expressed
Why is control of the gene expression important?
It determines how a cell will develop and how it will function once it is mature
What are enhancers like?
Switches on/off, up/down
Transcription factors
Proteins that bind to DNA and regulate genetic expression
What are many of these transcription factors that influence enhancers influenced by?
Signals received from the cell as it responds to the environment; thus, providing the mechanism for interaction of the environment and genes to influence development