Week 1: Diabetes Flashcards

1
Q

What is diabetes mellitus?

A

Metabolic condition that causes the inability to make or use insulin

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2
Q

What does insulin do?

A

transports glucose to body cells for growth/energy

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3
Q

Where is the hormone insulin produced?

A

pancreas

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4
Q

Type of DM where the pancreas is not working properly, or insulin is not used properly

A

Type 2 NIDDM

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5
Q

Type of DM causing diabetic ketoacidosis

A

Type 1 IDDM

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6
Q

Types of DM that is chronic state of hyperglycemia

A
  • Type 2 NIDDM

- gestational diabetes

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7
Q

Condition when body breaks down fats and proteins for energy leading to buildup of ketones

A

diabetic ketoacidosis

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8
Q

T/F

Gestational diabetes resolves after giving birth

A

True

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9
Q

T/F

DM can be seen with Down syndrome, klinefelters, turner’s syndrome

A

True

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10
Q

What is the leading cause of kidney failure in African Americans and American Indians?

A

Diabetes (from pdf posted)

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11
Q

90-95 % of diabetes cases are what type?

A

Type 2

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12
Q

List the 5 classifications of DM

A
  1. Type 1
  2. Type 2
  3. Gestational diabetes
  4. Other causes ( dmg pancreas, genetic conditions)
  5. Pre diabetes
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13
Q

Prediabetes occurs when someone has (2 things)

A

impaired glucose tolerance (IGT) or impaired fasting glucose (IFG)

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14
Q

Etiology of Type 1

A

autoimmune response where antibodies destroy beta cells (pancreatic insulin producing cells)

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15
Q

T/F

Type 1 is not genetically linked.

A

False

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16
Q

List 3 environmental factors that can trigger type 1.

A
  • viral infections
  • infant diet
  • exposure to toxins
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17
Q

T/F

Type 2 has stronger genetic predisposition than type 1.

A

True

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18
Q

5 factors that increase chance of type 2

A
aging
lack of physical activity
chronic stress
obesity
ethinicity
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19
Q

T/F

Men have a higher rate of type 2 than women.

A

True

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20
Q

T/F

Women have a higher rate of type 1 than men.

A

False

Men = women for type 1

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21
Q

T/F

Caucasians have highest rate of type 1

22
Q

polydipsia

A

increased thirst

23
Q

List 7 symptoms of DM

A
polydipsia
polyuria
polydysphagia
blurred vision
weakness
fatigue
dizziness
24
Q

Are these symptoms of type 1 or type 2?

  • unusual weight loss
  • Frequent skin, gum or bladder infections; cuts or bruises slow to heal;
  • Numbness/tingling in the hands or feet
  • Nephropathy & retinopathy , neuropathy
25
Are these symptoms of type 1 or type 2? - Keonuria - Weight loss, - muscle cramps, - irritability, - emotional lability (fluctuating moods), - headaches, anxiety
type 1
26
causes fruity odor breath, nausea, confusion, dry flushed skin, difficulty breathing
Keonuria
27
what is normal fasting blood glucose level?
< 100mg/dL
28
what fasting blood glucose level diagnosis diabetes? | What is the random blood glucose level?
``` fasting = > 126mg/dL random = > 200 mg/dL ```
29
Average concentration of glucose in the blood over a 6 week to 3 month time period? What level means hyperglycemia?
Hemoglobin A1C level > 6.5%
30
fatigue, drowsiness, seizure, shallow breathing are symptoms of?
hypoglycemia
31
These symptoms mean? thirst, heartburn, fast breathing, excessive urination, headache, blurred vision, abdominal pain, constipation, can lead to coma
hyperglycemia
32
T/F | Type 2 can have temporary remission 3-6 mo. after diagnosis
False | Type 1 does
33
BP for hypertension
140/90
34
common cause of HTN in type 2
obesity
35
common cause of HTN in type 1
diabetic nephropathy
36
List 4 macrovascular complications of DM
HTN cardiovascular disease CVA peripheral artery disease
37
Causes impaired wound healing & tissue hypoxia
peripheral artery disease (PAD)
38
List 2 microvascular complications of DM
diabetic retinopathy | diabetic nephropathy
39
affects multiple systems in the body and can occur w/in 1 year of type 2 DM diagnosis
diabetic autonomic neuropathy
40
leading cause of blindness in ages 18-75
diabetic retinopathy
41
most common complication w/DM pt
diabetic peripheral neuropathy
42
- affects GI system, sexual dysfunction (ED), genitourinary system. - can lead to CHF, silent MI - symptoms = exercise intolerance, resting tachycardia, orthostasis
diabetic autonomic neuropathy
43
pain in thighs and hips followed by weakness of LE proximal muscles; seen in elderly w/DM
Proximal Motor Neuropathy
44
Leading cause of end stage renal disease
diabetic nephropathy
45
Pain, tingling, burning, skin sensitivity LE>UE | are signs of?
diabetic peripheral neuropathy
46
Why does DM affect kidneys?
high blood sugar breaks down the filters causing substances like proteins to be excreted that should not be called microalbuminuria
47
What 4 things lead to diabetic foot complications?
1. Ulcers from repetitive stress 2. Autonomic neuropathy- dry cracked skim prone to ulceration and infection 3. Sensory polyneuropathy- can’t feel the wounds or breakdown 4. PAD- decreased circulation of blood
48
T/F | Type 1 can be cured.
False
49
What is metformin?
drug that decreases liver output of glucose for type 2 DM
50
T/F | Almost everyone with type 1 diabetes & most with type 2 will eventually have nonproliferative retinopathy.
True
51
T/F | People with DM are more likely to have cataracts and glaucoma.
True