Week 1 Flashcards

1
Q

4 most common cancers in the uk

A

breast
prostate
lung
bowel

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2
Q

7 types of diabetes medication and where they work on

A
DPP-4 inhibitors 
Incretin mimics (GLP-1-RA)
sulphonylurea
metformin
pioglitazones
sglt-2 inhibitor 
alpha-glucosidase inhibitor
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3
Q

example of dpp-4 inhibitor

A

gliptins, e.g. stigagliptin

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4
Q

example of incretin mimic

A

exenatide

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5
Q

route of administration for exenatide

A

IM injection

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6
Q

example of sulphonylurea

A

glipizide, glicazide

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7
Q

example of glitazones

A

pioglitazones

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8
Q

example of alpha-glucosidase inhibitor

A

acarbose

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9
Q

example of SGLT2 inhibitor

A

gliflozins, e.g. dapagliflozin

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10
Q

which diabetic drug has potential hypoglycaemia as side effect

A

sulphonylureas

incretin mimics

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11
Q

which diabetic drug has weight gain side effect

A

sulphonylurea

glitazones

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12
Q

which which diabetic drug has weight loss side effect

A

metformin
incretin mimics
sglt-2 inhibitors

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13
Q

which diabetic drug should be stopped in AKI and kidney failure?

A

metformin

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14
Q

which diabetic drug causes fluid retention?

A

glitazones

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15
Q

which diabetic drug causes flatulence

A

alpha glucosidase inhibitors

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16
Q

sites of actions of diabetic drugs (7)

A

incretin mimic on gut, pancreas
dpp-4 inhibitors on dpp-4, reduce incretin breakdown
sulphonylurea on beta islet cells
metformin on heptatocytes
pioglitazones on adipocytes
sglt-2 inhibitors on kidney
alpha-glucosidase on intestine transport proteins

17
Q

symptoms of delirium

A
change in cognition/memory
change on consciousness
hallucinations
mood disturbance
sleep disturbance
18
Q

causes of delirium

A

PINCH ME

pain
infection
nutrition
constipation
hydration

medication
environment

19
Q

where are pressure sores common

A
heels
sacrum
shoulder
back of head
elbows
20
Q

difference between urge and stress incontinence

A

stress incontinence causes leakage when intra-abdominal pressure is increased

urge incontinence is the sudden need to urinate without ability to hold.

21
Q

what is overflow incontinence

A

when a patient leaks urine due to blockage in the outflow tract, causing retention as well

22
Q

what are some medications that can cause urinary incontinence

A

ACEI
diuretics
anticholinergics
antiparkinsonism medication

23
Q

2 types of faecal incontinence

A

urge incontinence and passive incontinence