Week 1 Flashcards

1
Q

Pathology:

A

Study of disease

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2
Q

Medical specialty of Pathology:

A

To understand how Dx works -diagnose Dx by signs -Dx prevention

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3
Q

Pathology is the bridge between _____________ & ___________

A

Basic Science & Clinical Medicine

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4
Q

General Pathology:

A

Rxn of cells & tissues to injurious stimuli

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5
Q

Acute inflammation in response to bacterial infection…

A

General pathology

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6
Q

Deprivation of O2 / Hypoxic is an example of…

A

General pathology

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7
Q

Systemic Pathology:

A

Alterations & underlying mechanisms in diseases (organ specific)

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8
Q

Liver failure is an example of…

A

Systemic Pathology

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9
Q

Abnormal body process w/ or w/o characteristic signs

A

Disease

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10
Q

All disease begins at the…

A

Molecular & cellular level

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11
Q

Father of modern pathology…

A

Rudolph Virchow

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12
Q

-Biochemical alterations -Ultrastructural changes -Light microscopic changes -Gross morphological changes

A

Sequential development of biochemical & morphological changes due to cell injury

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13
Q

What are the 4 aspects of a disease?

A

1) Etiology 2) Pathogenesis 3) Molecular & Morphological changes 4) Clinical manifestations

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14
Q

_________ refers to the cause of the disease.

A

Etiology

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15
Q

Genetic (intrinsic) & Acquired (extrinsic) are…

A

The 2 major classes of etiology

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16
Q

________ refers to the mechanism of disease development.

A

Pathogenesis

17
Q

Pathogenesis sequence of events is from ________ stimulus to the ________ expression of the disease in the response of cells or tissues to the etiology

A

INITIAL & ULTIMATE

18
Q

_________ & _________ refer to biochemical & structural alterations induced by the cells & organs of the body

A

Molecular & Morphological Changes

19
Q

_________ _________: results of genetic, biochemical, & structural changes in cells & tissues

A

Clinical Manifestations

20
Q

Signs: Symptoms:

A

Animals- you as a clinician see Humans - what the patient feels and tells you

21
Q

Injury to cells & to extracellular matrix (ECM) lead to…

A

Tissue & organ injury

22
Q

_______: concise statement or conclusion concerning the nature, cause, or name of a disease

A

Diagnosis

23
Q

5 Types of Diagnosis (Dx)

A

-Clinical Diagnosis -Differential Diagnosis >> DDx -Morphological Diagnosis >> MDx -Etiological Diagnosis >> EDx -Clinical Diagnosis

24
Q

Clinical Diagnosis

A

Based on case Hx, clinical signs, & PE

25
Q

DDx

A

List of diseases that could account for the evidence or lesions of the case

26
Q

MDx

A

Based on predominant lesions in tissues Microscopic & Microscopic 1- location 2- distribution 3- severity 4- duration/time 5- nature

27
Q

5 Main types of Pathological Processes:

A

1) Degeneration / Necrosis 2) Inflammation & Repair 3) Tissue Deposits / Pigmentation 4) Circulatory Disorders 5) Disorder of Growth (adaptation vs. neoplasia vs. malformation)

28
Q

EDx

A

More definitive Dx & names the specific cause of the disease

29
Q

Clinical Pathological Diagnosis

A

Based on the changes observed in the chemistry of fluids & hematology

30
Q

Outcome/Course of a disease:

A

Prognosis (good, intermediate, poor)

31
Q

____________: characteristic or indicative of a specific disease

A

Pathognomonic

32
Q
A

Avian Poxvirus

33
Q
A

MDx: Rumenitis, multifocal, necrotizing, hemorrhagic, severe, w/ infarcts

Pathogenesis: Grain overload > rumenal acidosis > mucosal damage > opportunistic fungal infection > vasculitis > ischemia & mucosal ulceration

34
Q

3 wk old puppy

anorexia

dyspnea

abdominal pain

normal rectal temp

A

Canine Herpesvirus -1 (CHV-1)

MDx: multifocal, acute renal necrosis & hemorrhage

OR

multifocal, acute necrohemorrhagic nephritis