Week 1

Question 1

Pathology:

Answer 1

Study of disease

Question 2

Medical specialty of Pathology:

Answer 2

To understand how Dx works -diagnose Dx by signs -Dx prevention

Question 3

Pathology is the bridge between _____________ & ___________

Answer 3

Basic Science & Clinical Medicine

Question 4

General Pathology:

Answer 4

Rxn of cells & tissues to injurious stimuli

Question 5

Acute inflammation in response to bacterial infection…

Answer 5

General pathology

Question 6

Deprivation of O2 / Hypoxic is an example of…

Answer 6

General pathology

Question 7

Systemic Pathology:

Answer 7

Alterations & underlying mechanisms in diseases (organ specific)

Question 8

Liver failure is an example of…

Answer 8

Systemic Pathology

Question 9

Abnormal body process w/ or w/o characteristic signs

Answer 9

Disease

Question 10

All disease begins at the…

Answer 10

Molecular & cellular level

Question 11

Father of modern pathology…

Answer 11

Rudolph Virchow

Question 12

-Biochemical alterations -Ultrastructural changes -Light microscopic changes -Gross morphological changes

Answer 12

Sequential development of biochemical & morphological changes due to cell injury

Question 13

What are the 4 aspects of a disease?

Answer 13

1) Etiology 2) Pathogenesis 3) Molecular & Morphological changes 4) Clinical manifestations

Question 14

_________ refers to the cause of the disease.

Answer 14

Etiology

Question 15

Genetic (intrinsic) & Acquired (extrinsic) are…

Answer 15

The 2 major classes of etiology

Question 16

________ refers to the mechanism of disease development.

Answer 16

Pathogenesis

Question 17

Pathogenesis sequence of events is from ________ stimulus to the ________ expression of the disease in the response of cells or tissues to the etiology

Answer 17

INITIAL & ULTIMATE

Question 18

_________ & _________ refer to biochemical & structural alterations induced by the cells & organs of the body

Answer 18

Molecular & Morphological Changes

Question 19

_________ _________: results of genetic, biochemical, & structural changes in cells & tissues

Answer 19

Clinical Manifestations

Question 20

Signs: Symptoms:

Answer 20

Animals- you as a clinician see Humans - what the patient feels and tells you

Question 21

Injury to cells & to extracellular matrix (ECM) lead to…

Answer 21

Tissue & organ injury

Question 22

_______: concise statement or conclusion concerning the nature, cause, or name of a disease

Answer 22

Diagnosis

Question 23

5 Types of Diagnosis (Dx)

Answer 23

-Clinical Diagnosis -Differential Diagnosis >> DDx -Morphological Diagnosis >> MDx -Etiological Diagnosis >> EDx -Clinical Diagnosis

Question 24

Clinical Diagnosis

Answer 24

Based on case Hx, clinical signs, & PE

Question 25

DDx

Answer 25

List of diseases that could account for the evidence or lesions of the case

Question 26

MDx

Answer 26

Based on predominant lesions in tissues Microscopic & Microscopic 1- location 2- distribution 3- severity 4- duration/time 5- nature

Question 27

5 Main types of Pathological Processes:

Answer 27

1) Degeneration / Necrosis 2) Inflammation & Repair 3) Tissue Deposits / Pigmentation 4) Circulatory Disorders 5) Disorder of Growth (adaptation vs. neoplasia vs. malformation)

Question 28

EDx

Answer 28

More definitive Dx & names the specific cause of the disease

Question 29

Clinical Pathological Diagnosis

Answer 29

Based on the changes observed in the chemistry of fluids & hematology

Question 30

Outcome/Course of a disease:

Answer 30

Prognosis (good, intermediate, poor)

Question 31

\_\_\_\_\_\_\_\_\_\_\_\_: characteristic or indicative of a specific disease

Answer 31

Pathognomonic

Question 32

Answer 32

Avian Poxvirus

Question 33

Answer 33

MDx: Rumenitis, multifocal, necrotizing, hemorrhagic, severe, w/ infarcts Pathogenesis: Grain overload \> rumenal acidosis \> mucosal damage \> opportunistic fungal infection \> vasculitis \> ischemia & mucosal ulceration

Question 34

3 wk old puppy anorexia dyspnea abdominal pain normal rectal temp

Answer 34

Canine Herpesvirus -1 (CHV-1) MDx: multifocal, acute renal necrosis & hemorrhage OR multifocal, acute necrohemorrhagic nephritis