WEEK 1+2 Pancreas Plan

Question 1

Force and Fill ED

Answer 1

Force - entire structure to be one density
Fill - focusing on parts or bits of structure a certain density

Question 2

What kind of treatment unit is compatible with Monaco

Answer 2

Elekta

Question 3

What would you set as you statistical uncertainty

Answer 3

1% clinically
At uni, 3% is acceptable to speed up plan

Question 4

Number of control points

Answer 4

Max number is 360

Question 5

Kidney goals and toxicity

Answer 5

Mean <28Gy
V12<55%
Clinical dysfunction

Question 6

Bowel quantec tolerance and toxicity

Answer 6

V15<120cc
Grade 3+ toxicity

Question 7

Spinal cord quantec tolerance and toxicity

Answer 7

Max dose 50gy
myelopathy

Question 8

Stomach QUANTEC tolerance and toxicity

Answer 8

D100<45Gy
Ulceration

Question 9

Liver

Answer 9

Mean dose <30-32
RILD

Question 10

Oesophagus

Answer 10

Mean dose <34 gy
Grade 3+ oesophagitis

Question 11

Isoconstraint vs isoeffect

Answer 11

Isoconstraint - EUD you set
Iso effect - calculated EUD, what plan is achieving

Question 12

Layering

Answer 12

Put the most important objectives at the top

Question 13

Dose limiting constraints

Answer 13

Serial parallel - biological cost function to limit dose to OARs
Quadratic overdose - minimise hotspots and ensure uniform dose distribution
Overdose DVH - max DVH
Maximum dose

Question 14

Dose increasing constraints

Answer 14

Quadratic Underdose - establishes a minimum dose
Underdose DVH - min DVH

Question 15

Dose increasing objectives

Answer 15

Target EUD - uniform/min dose
Target penalty - uniform/min dose
These are NOT constraints

Question 16

Multicriterial

Answer 16

Let’s you specify that the overdose volume constraint can be a secondary objective as long as the primary target is not affected

Question 17

Femoral head and neck

Answer 17

D100<52GY
Necrosis