Week 1 Flashcards

1
Q

Define pain

A

An unpleasant sensory and emotional experience associated with actual or potential tissue damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What percentage of the population will experience chronic pain and severe chronic pain

A

Chronic pain = 20%
Severe chronic pain 3-5%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Define nociception

A

The natural mechanism by which an individual detects the presence of potentially tissue haeming stimulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the steps of noiciception?

A
  1. Transduction (stimulus detected by nerve)
  2. Transmission (signal travels up nerve)
  3. Modulation (occurs in the spinal root)
  4. Perception
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where are nociceptors found?

A

In the skin, bones, muscles, internal organs, blood vessels.
They are not found in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What types of nerve fibres are noicieptors?

A

Some Aß fibres (pain) and some C fibres (light touch & burning)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Explain pain gate control theory

A

C fibres carry pain signals to the ascending pain pathway. Inhibitory interneurons inhibit this signal to reduce the painful stimulus. Normal the C fibres inhibit the inhibitory interneurons, but Aß fibres can promote the inhibitory interneurons in the presence of touch/non painful stimulus.

This is why rubbing your knee after bumping it dulls the pain a little

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How do TENS machines work to dull pain?

A

They activate Aß fibres which promote inhibitory interneurons, which inhibitory pain signals in the ascending pain pathways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Explain descending modulation of pain

A

The peri aqueducts grey matter (PAG) receive signals from all over the brain and send signals down a descending pathway to the dorsal horn to inhibit painful stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the differences between neuropathic and nociceptive pain?

A

Neuropathic = nerve damage
Nociceptive = tissue damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are common descriptors are used to describe neuropathic pain?

A

Shooting
Burning
Tingling
Numbness
Electric shock - like

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe the LANSS pain scale

A

It is used to assess/ differentiate neuropathic from nociceptive pain:

5 questions:
- prickling, tingling, pins and needles
- colour change in skin
- abnormally sensitive
- electric shocks
- burning

2 signs:
- pain due to cotton wool
- pin-prick threshold altered

Measured on scale of 24. A score over 12 usually indicates neuropathic pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Differentiate somatic vs visceral pain

A

Somatic:
- Well defined location
- sharp/aching pain
- constant

Visceral:
- vague localisation
- dull/cramp pain
-periodic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Explain how herniated IVD can cause lower pack pain

A

A herniated disc can press on the afferent nerve root and/or the herniated disc can activate local nociceptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is radicular back pain?

A

Pain that begins in the back and radiates down the lower limbs in a narrow band (not the same as refferd pain)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How is pain clinically assessed?

A

History, physical examination and investigations.

Defining the characteristics (SOCRATES)

Explore the quality of life impacts and ideas/concerns/expectations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Describe the brief pain inventory (BPI)

A

The BPI assess the impact of pain on day to day activities like walking, sleep, socialising, mood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the 6 Ps of pain treatment

A

-prevention (care, excerise, stretching)
- pathology (splint, antibiotics, etc)
- physical therapies
- pharmacology
- procedural (local analgesia)
- psychological

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the steps in the WHO analgesic ladder?

A

Step 1 - Non opiods (paracetamol & NSAIDs)

Step 2 - weak opiods (codeine, dihydrocodein)

Step 3 - strong opiods (morphine, fentanyl)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the side effects of opiods?

A

Sedation, constipation, insomnia, nausea, respiratory depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are the side effects of paracetamol?

A

Liver damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What are the side effects of NSAIDs?

A

GI ulceration, bleeding, renal damage

23
Q

What are the red flag symptoms of back pain?

A
  • Weight loss
  • fever
  • anatomical change
  • possible history of trauma
  • cauda equivalent syndrome symptoms (incontinence, loss of sensation in leg/perineal area)
24
Q

What are the 4 main lobes of the brain?

A
25
Q

What is a sulcus?

A

A groove in the brain

26
Q

What is a gyrus?

A

A fold in the brain

27
Q

what 2 sulci are important anatomical land marks?

A
  • Central sulcus
  • Lateral sulcus
28
Q

What are these Gyri and what do they do?

A
29
Q

What are these areas and what are there functions?

A

Broccas area = motor aspect of speach

Wernike’s area = language comrehension

30
Q

What is this structure?

A
31
Q

These parts make up the basal ganglia. Name them

A
32
Q

What is this section of the brain called and what processes is it involved in?

A

The hippocampus

Involved in memory and learning

33
Q

What is this part of the brain called and how can it be divided up?

A

The corpus callosum

It can be dived into the splenium (posterior), the body, the Genu (anterior), and the rostrum

34
Q

Name these structures

A
35
Q

What are the sensory and motor pathways in the spinal cord?

A

Dorsal column medial lemniscus = touch

Spinothalamic = pain

Corticospinal = motor control

36
Q

What is the difference between ascending (sensory) and descending (motor) pathways in the brain?

A

Ascending pathways relay in the thalamus

Motor pathways bypass the thalamus

37
Q

What fan like structure connects the cortex to the entrance/exit of the internal capsule?

A

The corona radiata

38
Q

what structure lie just beneath the temporal love?

A

The insula cortex

39
Q

Name these parts of the internal capsule

A
40
Q

During embryological development, what do the dorsal and ventral horns grow from

A

Alar plate => Dorsal horn

Basal plate => Ventral horns

41
Q

What is A-alpha fibres function?

A

Proprioceptors and motor nerves

42
Q

What is A-Beta fibres function?

A

Mechanoreceptors of the skin (feel regular touch)

43
Q

What is A-Delta fibre function?

A

Pain and temperature

44
Q

What is the function of C fibres?

A

Temperature, pain itch

45
Q

Where do afferent and efferent fibres leave/enter the spinal cord?

A

Dorsal horn = Afferent

Ventral horn = efferent

(DA VE)

46
Q

name the white matter tracts in the spinal cord

A
  • Dorsal funiculus
  • Later Funiculus
  • Ventral Funiculus
47
Q

What is the venous supply of the spinal cord?

A

Baston venous plexus

48
Q

Describe the arterial supply to the spinal cord

A

branches from the intercostal arteries form the radicular artery, which then branch into a anterior spinal artery and 2 posterior spinal arteries

49
Q

what structure marks the end of the spinal cord?

A

The spinal cord ends at the conus medullaris and becomes the cauda equina

50
Q

What is the role of the dorsal column medial lemniscus pathway, and describe its path through spinal cord

A

Discriminative touch

Afferent nerve reaches spinal cord and splits. One branch enters the dorsal root and the other travels up the spinal cord. It desiccates at the midbrain. then relays at the thalamus before entering the sensory cortex.

51
Q

What is the role of the spinothalamic pathway and describe its pathway through the spinal cord.

A

Pain, Temperature, Crude touch

The enter the dorsal root horn and immediately synapses and desiccates before traveling up to the thalamus where it synapses again and goes onto the sensory cortex

52
Q

Which pathway innervates the cranial nerves and describe its pathway?

A

corticobulbar pathway

Travels from the cortex to the cranial nerve nuclei

53
Q

What is the role of the corticospinal pathway and describe its pathway through the spinal cord

A

Volountary motor control

Descends from the cortex to the medulla where 85% of fibres decussate.

54
Q

What is the role of the reticulospinal pathway?

A

Involuntary control (posture/balance) of muscles

Pontine tracts = extensors

Medullary tract = Flexors