Week 1 Flashcards
How are the senses of taste and smell stimulated
Buy chemoreceptors (sensory receptor cells) binding to particular chemicals
Function of taste and smell
Protects us from poisons / spoiled food
Influences the flow of digestive juice
Smell can influence taste
Where are the sensory receptor cells for taste mainly packaged in
Taste buds
What does a taste bud consist of
Taste receptor cells
Support cells between taste receptor cells
Basal cells
Afferent nerve fibres
How long is the life span of taste receptor cells and what happens when it dies
10 days
Basal cells will differentiate into new taste receptor cells and replace the old one
Where are taste buds located at
Tongue
Pharynx
Epiglottis
Palate
Where are taste buds mostly located at
In papillae in the tongue
What are papillae seen as on tongue
Raised bumps or little red dots
4 types of papillae
Filliform
Fungiform
Vallate
Foliate
Which papillae contain taste buds
Fungiform
Vallate
Foliate
Which papillae is the most abundant
Filliform but it does not contain taste buds
How does action potentials travel from taste receptor cells to the brainstem
- Chemicals trigger the Taste receptor cells to produce action potentials
- Action potentials travel through the afferent nerve fibres
- to cranial nerves (V / IX / X)
- Action potential is then conveyed by the cranial nerves to cortical gustatory areas
What is cortical gustatory areas
Region of cerebral cortex responsible for the perception of taste
What are the cranial nerves involved in transmitting signals from afferent taste nerve fibres
Chorda tympani branch of facial nerve CN VII
Glossopharyngeal nerve CN IX
Vagus nerve CN X
Taste signals from where are conveyed to the brainstem via chorda tympani branch of facial nerve
Anterior 2/3 of the tongue (innervated by chorda tympani)
Taste signals from which part are conveyed to the brainstem via glossopharyngeal nerve
posterior 1/3 of the tongue
Taste signals from which part are conveyed to the brainstem via vagus nerve
Epiglottis
Pharynx
Why may patients who had undergone middle ear surgery experience an alteration to sense of taste
Because the facial nerve is closely related to the middle ear hence if it can damaged during the surgery and taste will be altered
What is bitter taste stimulated by
Alkaloids
Poisonous substances
toxic plant derivatives
What is the sour taste stimulated by
High amounts of free H+
What is the salty taste stimulated by
NaCl
What is the sweet taste stimulated by
Glucose
What is umami taste stimulated by
Amino acids especially glutamine
What is ageusia
Loss of taste
What can cause ageusia
Nerve damage
Glossitis
Radiation
Tobacco
Endocrine disorders
What is hypogeusia
Reduced taste function
What can cause hypogeusia
Chemotherapy
Medications
What is dysgeusia
Distortion of taste
Causes of dysgeusia
Glossitis
Gum infections
URTI
Medications
Chemotherapy
Neoplasms
Zinc deficiency
What are the 2 main cranial nerves involved in the sense of smell
Olfactory Nerve CN I
Trigeminal Nerve CN V
What is the difference between the types of smells that each cranial nerve is involved in
CN I is involved in common odours such as rose, chocolate, mint whereas CN V is involved in chemical stimulus such as smells that irritates you (ammonia) , burning, cooling
If you smelled something harmful, which nerve is involved to stop inhalation and why does it do it
CN V (trigeminal)
to protect the lungs
Where is the olfactory neuroepithelium located at
At the top of each nasal cavity
Does all the air breathed in reaches the olfactory neuroepithelium
No, only 10-15% reach the neuroepithelium. Most of the air goes down the nasopharynx into the airways
How is the smell of the food enhanced by swallowing
Due to retrograde airflow from the nasopharynx back to the nasal cavity
How does air reach the olfactory mucosa during quiet breathing
Because the olfactory mucosa is above the normal path of airflow, the air reaches above by diffusion
How does sniffing enhance smelling
Draws air currents upwards to the olfactory mucosa
What features does a substance must have in order to be smelled
Volatile
Water soluble
Why does the substance need to be water soluble in order to be smelled
So it can dissolve in the mucous which coats the olfactory mucosa
Function of the mucous coating the olfactory mucosa
Ensures moist environment and protection
Disperses odour substances to the olfactory receptors