Nose Flashcards
What is allergic rhinitis
IgE mediated allergic reaction
Which type of hypersensitivity is allergic rhinitis part of
Type 1 immediate hypersentivity- since it is IgE mediated
What is considered as intermittent allergic rhinitis
Symptoms <4 days per week or symptoms <4 weeks
What is considered as persistent allergic rhinitis
Symptoms >4 days per week AND symptoms >4 weeks
Common triggers for intermittent allergic rhinitis
Grass pollen
Tree pollen
Fungal spores
common triggers for persistent allergic rhinitis
House dust mite
Cats
Dogs
Allergic rhinitis is often associated with
Allergic conjunctivitis
An atopic patient with allergic rhinitis is likely to
Also have atopic eczema / asthma / allergic conjunctivitis
Symptoms of allergic conjunctivitis
red eyes
puffy eyes
watery discharge
Symptoms of allergic rhinitis
Sneeze
Nasal itching
Nasal discharge
Nasal congestion
Allergic crease
What is allergic crease
hyper pigmented skin line on nose caused by constantly rubbing the nose in an upwards motion = indicates repeated itching of nose
Investigations for allergic rhinitis
Clinical - symptoms may show seasonal variation
IgE level, skin prick test if in doubt
Management for mild allergic rhinitis
Avoid allergen
Nasal irrigation
Oral / intra-nasal anti-histamines
Intranasal chromone if antihistamine is contraindicated
Management for moderate-severe allergic rhinitis
Intranasal steroids
Intranasal steroids + oral antihistamines if symptoms persist
Short course oral steroids if severe, uncontrolled symptoms significantly affecting quality of life
Example of intranasal antihistamine used for allergic rhinitis
Azelastine
Example of oral anti-histamines
Loratadine
Cetirizine
What is used for a patient with allergic rhinitis if topical antihistamine is contraindicated
Intranasal chromone - sodium cromoglicate
Example of intranasal steroids
Mometasone furoate
Fluticasone furoate
Beclometasone
What is non-allergic rhinitis
inflammation of the inside of the nose that is not caused by an allergy
Causes of non-allergic rhinitis
Infections - viral
Vasomotor rhinitis
Occupational rhinitis
Hormonal rhinitis
Drug-induced
What is vasomotor rhinitis
Non-allergic rhinitis due to parasympathetic overdrive (autonomic dysfunction)
Triggers of vasomotor rhinitis
Chemical irritants
Changes in weather
Excess humidity
Very dry atmosphere
Stress
What is occupational rhinitis
Non-allergic rhinitis symptoms only occur in workplace due to inhaled irritants such as latex, wood dust
What drugs can cause drug induced rhinitis
ACEi
Beta blockers
NSAID
Cocaine
Symptoms of non-allergic rhinitis
Runny nose, clear discharge
Sneezing
Itchy nose
Nasal congestion
Management of non-allergic rhinitis
Supportive for viral cause
Avoid triggers
Consider anticholinergics for vasomotor rhinitis
Complications of non-allergic rhinitis
Sinusitis
Nasal polyps
What is acute sinusitis
Inflammation of paranasal sinuses with symptoms lasting less than 12 weeks
Acute sinusitis can be preceded by
Rhinitis
Viral URTI
Dentition
Acute sinusitis is most commonly preceded by
Rhinitis
Causative pathogens of acute sinusitis
Strep pneumoniae
H influenza
Moraxella catarrhalis
Symptoms of acute sinusitis
Nasal blockage / discharge + facial pain/pressure
Pain worse when bending / leaning forward
Reduction of smell
Investigations for acute sinusitis
Clinical
Management for acute sinusitis
Analgesics
Nasal decongestants
Saline irrigation
High dose intranasal steroids if symptoms > 10 days
Antibiotics if severe
What antibiotics are used for severe acute sinusitis
- Phenoxymethylpenicillin
- Doxycyline
Contraindication of doxycycline
Children under 8 years old because it can cause discoloured teeth, photosensitivity
Complications of acute sinusitis
Orbital cellulitis
Periosteal abscess - Pott’s puffy tumour
Thrombosis of cavernous sinus
Thrombosis of superior sagittal sinus
Osteomyelitis
What is chronic sinusitis
Painless sinusitis causing bilateral nasal obstruction due to mucosal hypertrophy with purulent discharge
Management of chronic sinusitis
intranasal corticosteroids
nasal irrigation with saline solution
What may suggest that this condition isn’t sinusitis
If nasal blockage is unilateral
What are nasal polyps
Painless, non-cancerous growths on the lining of nasal or sinus passages
Are nasal polyps common in children
No
Causes of nasal polyps
Non-allergic rhinitis
Allergy
infection
Aspirin sensitivity
Nickel exposure
Cystic fibrosis
Symptoms of nasal polyps
Nasal obstruction
Runny nose
Reduced sense of taste or smell
Investigations for nasal polyps
Nasoendoscopy
Management of nasal polyps
Topical steroids
Routine ENT referral
ENT symptoms of granulomatosis with polyangiitis
Sinusitis
Epistaxis
Mouth ulcers
Sensorineural hearing loss
Saddle nose deformity
Otitis media
Management of GPA
If early - methotrexate + steroids
If late - IV cyclophosphamide + steroids
What are the benign lesions of the nose
Squamous cell papillomas
Sinonasal papillomas
Recurrent respiratory papillomatosis
Which benign lesion is the most common
Squamous cell papilloma
Sinonasal papillomas tend to occur in patients who are
Over 50
Male
Subtypes of sinonasal papillomas
Inverted
Exophytic
Oncocytic
Where are inverted sinonasal papillomas located at
Lateral walls / paranasal sinuses
Where are exophytic sinonasal papillomas located at
Lateral walls / paranasal sinuses
Where are oncocytic sinonasal papillomas located at
Nasal septum
What is recurrent respiratory papillomatosis
Papillomas occurring at aerodigestive tract
What does the aerodigestive tract consist of
Airway (nasal cavity -> lungs)
Oesophagus
Recurrent respiratory papillomatosis is associated with
HPV
Recurrent respiratory papillomatosis usually presents in
Children, causing hoarse voice and progressive SOB
What are the malignant lesions in the nose
Squamous cell carcinoma
Nasopharyngeal carcinoma
Primary adenocarcinoma
Neuroblastoma
Lymphoma
Which type of malignant lesion of the nose is the most common
Squamous cell carcinoma
Risk factors of nasopharyngeal carcinoma
Males
Far east descent
EBV
HPV
Volatile nitrosamines in food
Smoking, alcohol
Family history
Examples of food that has volatile nitrosamines
Cured meat
Beer
Processed fish
How aggressive is nasopharyngeal carcinoma
Highly aggressive - extensive local spread and early metastasis
What is subglottic stenosis
Narrowing of the airway below the vocal cords and above the trachea
Cause of subglottic stenosis
Idiopathic
May be associated with vasculitis in adults
Symptoms of subglottic stenosis
Progressive breathing difficulty
Breathing difficulty exacerbated by exertion
Management of subglottic stenosis
Division of stenosis
Resection and reconstruction if severe