WBCs Flashcards
proportions in blood, granular vs agranular, nucleus appearance, function
neutrophils
-granular
-60-70% of all WBCs
-stained by neutral dyes
-multi-lobed nucleus
-function: phagocytosis and chemical destruction of microbes; first responders to injury or infection
eosinophils
-granular
-2-4% of all WBCs
-stained by acidic dyes
-bi-lobed nucleus
-function: defend against parasitic infections, involved in allergic reactions by combatting effects of histamine, and phagocytosis of antigen-antibody complexes
basophils
-granular
-less than 1% of all WBCs
-stained by basic dyes
-bi-lobed nucleus (surrounded by large, dark granules
-function: release histamine and other inflammatory chemicals; involved in allergic responses
monocytes/macrophages
-agranular
-3-8% of all WBCs
-large, horseshoe-shaped nucleus
-functions: phagocytosis (as a fixed or wandering macrophage)
lymphocytes
-agranular
-20-25% of all WBCs
-large, round nucleus
-function: adaptive immunity; B-cells produce antibodies, T-cells mediate cellular immunity, and natural killer (NK) cells destroy virus-infected and cancerous cells