WBC NON-NEOPLASTIC DISORDER

Question 1

Normal Relative neutrophil count in adults, bands PLUS segmented forms, is approximately 50% to 70%

TRUE OR FALSE

Answer 1

TRUE

Question 2

Neutropenia is defined as a decrease in the ANC to less than 2.0 X 109 /L in white adults or 1.3 X 109 in black adults

Answer 2

TRUE

Question 3

What are the 2 quantitative WBC disorders?

Answer 3

Leukopenia and leukocytosis

Question 4

Leukopenia is ______ leukocytosis is _______

Answer 4

decrease and increase

Question 5

Pertaining to the formation of tumors by the uncontrolled proliferation of cells; benign or malignant

Answer 5

Neoplastic

Question 6

What are the usual suspects when your total WBC is low?

Answer 6

Neutrophils & Lymphocytes

Question 7

An increase in total number of white cells per liter of blood exceeds the higher limit of normal in peripheral blood due to any cause

Answer 7

Leukocytosis

Question 8

What is the value for leukocytosis, in numerical value?

Answer 8

11,000/cmm

Question 9

Normal range of white cell count

Answer 9

5,000-11,000/cmm

Question 10

What is a Physiological cause of leukocytosis?

Answer 10

Newborn, pregnancy

Question 11

Increased production in the marrow, increased release from marrow stores, decreased margination, and decreased extravasation into tissues are all mechanisms and causes of?

Answer 11

Leukocytosis

Question 12

Allergic disorders due to Asthma, hay fever, drug reaction to penicillin, parasitic infections, skin diseases such as pemphigus, dermatitis herpetiformis, Certain malignancies such as Hodgkin lymphoma, and Collagen vascular diseases are causes of?

Answer 12

Eosinophilia

Question 13

What are 2 markers of chronic inflammation in monocytosis?

Answer 13

Chronic infections and inflammation

Question 14

Chronic infections
* Tuberculosis, bacterial endocarditis
Chronic inflammation
* Ulcerativecolitis
* Collagen vascular diseases (SLE- Systemic lupus erythematosus)
These are markers of?

Answer 14

Monocytosis

Question 15

What should be ruled out if you suspect a LEUKEMOID REACTION?

Answer 15

CHRONIC MYELOGENOUS LEUKEMIA

Question 16

MONOCYTOPENIA

Answer 16

Monocytes <2.2 x 109/L

Question 17

Eosinopenia is defined as an absolute eosinophil count of less than _______X 109/L

Answer 17

0.09

Question 18

Children between 2 weeks and 8 to 10 years of age have higher absolute lymphocyte counts than adults with an absolute lymphocyte count greater than ______X 109/L

Answer 18

10.0 or 10

Question 19

. genetic conditions causing mutation to STAT3 causes what quantitative WBC abnormality?

Answer 19

• Eosinophilia

Question 20

What quantitative Non-neoplastic abnormality can be expected in patients taking anti-cancer medications?

Answer 20

• Neutropenia

Question 21

When there is suspected leukemoid reaction, chronic lymphocytic leukemia should be ruled out

TRUE OR FALSE

Answer 21

FALSE

Question 22

Cytokine stimulation from IL-3 and IL-5 in adults causes this finding in the WBC count:

Answer 22

• Eosinophil count of 3 X109/L

Question 23

Eosinophilia is defined as an absolute eosinophil count greater than ________X109/L

Answer 23

0.4

Question 24

In rodaks, agranulocytosis refers to a neutrophil count of less than _____X 109/L

Answer 24

0.1

Question 25

Give me 1 infectious disease causing monocytosis

Answer 25

MALARIA

Question 26

Lymphocytosis in adults is greater than ______X109/L

Answer 26

5.0 or 5

Question 27

What can cause profound monocytopenia?

Answer 27

hair cell leukemia

Question 28

. Provide 1 condition causing immune neutropenia

Answer 28

NEONATAL ALLOIMMUNE NEUTROPENIA

Question 29

Neutropenia is defined as a decrease in the ANC to less than _______ in white adults or _____ in black adults

Answer 29

2.0 X 109 /L and 1.3 X 109

Question 30

Normal Relative neutrophil count in adults, bands PLUS segmented forms, is approximately 50% to 70% TRUE OR FALSE

Answer 30

TRUE