WBC

Question 1

nucleated cells that function in body defense

Answer 1

white blood cells

Question 2

reference range
adult:
nb:

Answer 2

adult: 4 500-11 000/uL
nb: 13 500-38 000/uL

Question 3

conversion from mm3 to uL

Answer 3

move the decimal point 3 places to the left

Question 4

predominant WBC in an adult

Answer 4

neutrophil

Question 5

predominant WBC in <4 years of age

Answer 5

lymphocyte

Question 6

whats the most valuable and reliable criterion in determining WBC maturity

Answer 6

nuclear chromatin pattern

Question 7

earliest recognizable granulocytic precursor

Answer 7

myeloblast

Question 8

type of myeloblast:

• no granules
• large nucleus, little cytoplasm
• 2 to 4 nucleoli
• slightly basophilic

Answer 8

type 1 myeloblast

Question 9

type of myeloblast:

• dispersed primary granules
• <20 granules/cell

Answer 9

type 2 myeloblast

Question 10

type of myeloblast:

• > 20 granules/cell
• rare in BM

Answer 10

type 3 myeloblast

Question 11

only exemption in the cell size rule

Answer 11

promyelocyte

Question 12

indicator of normal promyelocyte

Answer 12

hof

Question 13

hollow in the cytoplasm of a cell that lodges the nucleus

Answer 13

hof

Question 14

stage of synthesis of WBC primary granules

Answer 14

type 2 myeloblast

if above is not on the choices, answer is promyelocyte

Question 15

last WBC stage capable of mitosis

Answer 15

myelocyte

Question 16

WBC stage where synthesis of secondary granules occur

Answer 16

myelocyte

Question 17

phenomenon that describes the appearance of secondary granules near the area of golgi apparatus

Answer 17

dawn of neutrophilia

Question 18

type of myelocyte where patches of grainy pale pink cytoplasm representing secondary granules start to become obvious

Answer 18

early myelocyte

Question 19

type of myelocyte where nucleus has considerably more heterochromatin

Answer 19

late myelocyte

Question 20

other name for metamyelocyte

Answer 20

juvenile cell

Question 21

WBC stage where synthesis of tertiary/gelatinase granules occur

Answer 21

metamyelocyte

Question 22

first stage of nuclear indentation

Answer 22

metamyelocyte

Question 23

metamyelocyte indent:

Answer 23

peanut/kidney

Question 24

band cell indent:

Answer 24

sausage

Question 25

metamyecolyte is seen in PBS is this normal?

Answer 25

no. only band cells may be considered normal

Question 26

youngest granulocytic precursor to normally appear in the

peripheral blood

Answer 26

band/stab cell

Question 27

should band cells be reported the same with neutrophils?

Answer 27

yes, according to CLSI

Question 28

secretory granules start to form in this WBC stage

Answer 28

band cells

Question 29

neutrophil normal value

Answer 29

1.6-9.2 x 10^9/L

Question 30

physiologic neutrophilia

Answer 30

exercise, nausea, vomiting, stress, pregnancy

Question 31

agranulocytosis value

Answer 31

< 0.5x10^9

Question 32

neutropenia associated drugs

Answer 32

amidopyrine, cephalosporin