Water transport osmosis Flashcards
Total Body Water (TBW)
60% of body weight. Further divided into 2/3 intracellular fluid and 1/3 extracellular fluid.
Edema
pathophysiological shift of fluid from the intravascular to extravascular compartment and indicates an increase in TBW measured as an increase in body weight.
aquaporins
water molecule specific channels. facilitated diffusion. much faster than water transport by simple diffusion
osmosis
process of net movement of water caused by a concentration difference of water between two compartments. occurs via simple or facilitated diffusion. never goes against concentration gradient.
osmolarity
sum total of all the solute concentrations in a compartment. high osmolarity means water concentration is low. low osmolarity means water concentration is high.
rate of net solute diffusion across the membrane is dependent
upon the magnitude of the solute concentration gradient across the membrane
osmotic pressure
amount of pressure that would have to be applied to force water back into its original chamber. result of water moving down its osmotic gradient until two chambers are in equilibrium.
magnitude related to solute concentration. greater in more concentrated solutions.
hydrostatic pressure
The pressure exerted by a fluid at equilibrium at a given point within the fluid, due to the force of gravity. Hydrostatic pressure increases in proportion to depth measured from the surface because of the increasing weight of fluid exerting downward force from above
isotonic (iso-osmolar)
solution with osmotic pressure or osmolarity equal to plasma (300 mOsm/kg)
hypertonic (hyper-osmolar)
solutions with a greater osmolarity than plasma
hypotonic (hypo-osmolar)
solutions with less osmolarity than plasma
response to cell shrinking
shrinkage activates two ion transporters, and ions enter the cell. by osmosis, water enters the cell, returning it to normal.
response to cell swelling
swelling activates two sets of pathways and ions leave the cell. by osmosis, water leaves the cell returning it to normal.