Water

Question 1

what are the 4 properties of water?

Answer 1

1. polarity
2. hydrogen bond formation
3. solvent properties
4. colligative properties

Question 2

what is the dipole moments of water ?

Answer 2

the dipole moments of water is 1.8 D

Question 3

what are the 3 things water is good at dissolving ?

Answer 3

its good at dissolving polar solvent and charged things
1. AA’s & Peptides
2. small alcohols
3.carbohydrates

Question 4

why is water good at dissolving polar and charged molecule but non polar

Answer 4

they have the ability to form H-bonds that increase the solubility whiles non polar molcules are hydrophobic due to entropy

Question 5

what is the hydrophobic effect

Answer 5

it is the association or folding of non polar molecules in aq sln. both on enthalpy and entropy decreases

Question 6

what are the 4 reasons that make the hydrophobic effect key ?

Answer 6

1. protein folding
2. protein-protein association
3. formation of lipid molecules
4. binding of ligand steroid hormones

Question 7

what is the mechanism of the hydrophobic effect ?

Answer 7

water molecules forms a cage shape around the non polar solute and new hydrogen bonds are formed due to the decrease in entropy of water in the presence of a non polar solute

Question 8

why is the hydrophobic effect key for ligand binding ?

Answer 8

it is key as binding sites in enzymes and receptors are usually hydrophobic and allow the binding of hydrophobic ligands like steriods hormone

Question 9

why is the hydrophobic affect key for protein folding & membrane formation?

Answer 9

the hydrophobic part of side chains are buried during protein folding and are not exposed to the solvent