W7L3 mutation and selection balance and response to selection Flashcards
Selection in perspective to evolution
Selection is the strongest evolutionary force acting within population and leading to a loss of genetic diversity.
The conceptual frame work of evolutionary process
Selection on genotypes within a population
Wright’s Formula of selection
Calculating the change in p in after a generation
Under Hardy-Weinberg equilibrium, what is the expected genotypic
frequency after selection?
Extension of Wright’s Formula to one locus with multiple alleles
Complex case of two loci with linkage (Kimura 1956)
The Theorems of Natural Selection
Assumption from the Breeder equation
The response to selection is rarely straightforward and is ALWAYS less than the selection differential applied.
This relationship is called the Breeder’s equation which predicts how a population will respond to selection under the hypothesis of linear selection.
The Breeder’s equation Based on the response to selection over one generation
The Breeder’s equation:
challenge for modelling different types of selection
Fisher’s Geometric Model
What does fisher geometric model do