W2L14 Cardiometabolic Syndrome

Question 1

What % of Australians have diabetes?

Answer 1

7%

Question 2

What random blood glucose parameters say that you have diabetes?

Answer 2

two RBGs above 11.1 mmol/L

Question 3

What fasting blood glucose level is indicative of diabetes?

Answer 3

Fasting glucose above 7 mmol/L

Question 4

What is the population and diabetic target for serum cholesterol?

Answer 4

pop <5.5 mmol/L

diabetes= 4 mmol/L

Question 5

What is the population target for LDL?

Answer 5

3 mmol/L

Question 6

What is the definition of the metabolic syndrome?

Answer 6

Abdominal obesity + 2 or more of:

• Elevated TG (> 1.7 mmol/L) and/or
• low HDL-C (< 0.9mmol/L [M];130/85 mmHg) or treatment

• Hyperglycaemia (FPG>5.6mmol/l
or IGT or diagnosed type 2 diabetes).

Question 7

What are the cut-offs for abdominal obesity?

Answer 7

Waist circumference:
• Europoids (>94 cm M; >80 cm F);
• South Asia & Chinese (>90 cm M; >80 cm F)

Question 8

What is the prevalence of metabolic syndrome in Australia?

Answer 8

34%

Question 9

Does abdominal obesity increase the risk of MI?

Answer 9

Yes (odds ratio of 2.22)

Question 10

Does increasing the number of components of the metabolic syndrome predict increasing risk of CHD and diabetes?

Answer 10

Yes

Question 11

What 2 skin conditions does hyperinsulinaemia pre-dispose to/

Answer 11

acnthosis nigricans: increased pigmentation in skin fold areas, and skin tags (insulin is a growth factor)

Question 12

What are the relevant parameters on a CV risk calculator?

Answer 12

Diabetes
Smoking status
Gender
Systolic BO
Total cholesterol: HDL ratio

Question 13

Who should not use a CV risk calculator? (Hint- patient is already at high risk)

Answer 13

• Existing cardiovascular disease.
• A strong family history of premature
cardiovascular disease.
• Patients with renal disease