W2L12 Introduction to Cancer Medicine

Question 1

Which kinds of metastatic cancers are curable? (3)

Answer 1

Testis cancer, lymphoma, leukemia

Question 2

What kind of localised cancer is incurable?

Answer 2

Glioblastoma

Question 3

What are the 10 ‘hallmarks of cancer’?

Answer 3

Sustained proliferative signalling
Evading grown suppressors
Avoid immune destruction
Enable replicative immortality
Tumour-promoting inflammation
Activation of invasion and metastasis
Induction of angiogenesis
Genome instability and mutation
Apoptosis resistance
Deregulated cellular metabolism