Vulvar D/O

Question 1

Most common cause of vulvar itching in children?

Answer 1

Atopic vulvitis

Remember lichen sclerosus occurs at any age too!!!

Question 2

Definition of recurrent vaginal candidiasis?

Answer 2

More than 6 attacks per year

Question 3

First line treatment for lichen sclerosus?

Answer 3

0.05% Clobetasol propionate over 3 months

-potent topical steroid therapy

Question 4

Second line treatment for lichen sclerosus if pt is steroid resistant? MOA?

Answer 4

Immunosuppressive therapy with tacrolimus or pimicrolimus.

Decreases immune function of the lymphocytes thus decreasing inflammation.
Verus steroids have anti-inflammatory and immunosuppressive properties by altering lymphocyte differentiation and function thus inhibiting cytokine production