Vulva Flashcards
Patjologic Diseases in Vulva (5)
Bartholin Cyst Nonneoplastic epithelial disorders Benign epithelial lesions Squamous neoplastic lesions Glandular neoplastic lesions
Cystic dilation of the bartholin gland due to obstruction
Bartholin cyst
Lining of Bartjolin cyst
Squamous or transitional epithelium
Other findings in bartjolin cyst
Infection/adenitis
Abscess formation
Epidemiology of Bartholin cyst
40 years old
Done to rule out malignancy in Bartholin cyst
Biopsy
Noneoplastic epithelial disorders (2)
Lichen sclerosus
Squamous hyperplasia
3 parameters to differentiate lichen sclerosus and squamous hyperplasia
Gross
Histology
Clinical Significance
Gross of lichens sclerosis
Leukoplakia
Histology of Lichen Sclerosus (5)
Thinning of the epidermis Basal cell degradation Hyperkeratosis Sclerotic change of the superficial dermis Dermal lymphocytic infiltrate
Histology of Squamous Hyperplasia
Acanthosis
Hyperkeratosis
Dermal lymphocytic infusion
Mitosis evident
Clinical sign of lichen sclerosus
Inc risk of vulvar ca
Clinical significance of squamous hyperplasia
Found at margins of vulvar ca
Benign epithelial lesion
Condyloma acuminata
Benign genital wart
Condyloma acuminata
Causative agents of condyloma acuminata
HSV 6, 11
Histology of Condyloma Acuminata
Exophytic papillary architecture
Acanthosis
Hyperkeratosis
Nuclear atypia with perinuclear halo seen in condylomata acuminata
Koilocytosis
Squamous Neoplastic Lesion of the Vulvs
Vulvar Squamous Cell Carcinoma
Two types and epi of vulvar squamous cell carcinoma
HPV related - 30%
NON HPV related- 70%
Premalignant lesion of hpv related vscc
Vulvar intraepithelial neoplasia
Premalignant lesion of non hpv related vscc
Diff vulvar intraepithelial neoplasia
Glandular Neoplastic Lesions (2)
Papillary Hidradenoma
Extramammary Paget Disease
Resembles intraductal papilloma of breast
Papillary Hidradenoma
