Vomiting Child Flashcards

1
Q

Describe gastroenteritis and key points

A
  • GE is a very common cause of vomiting in children but vomiting is a non-specific symptom, so ask yourself - what else could it be?
  • The mother is always right – if she is worried you should be too
  • Initial management is always ABC DEFG
  • Choose IV fluid & rate carefully, use 0.9% saline with 5% glucose and KCL 20mmol/l for rehydration
  • If your diagnosis & management are right, the child should improve
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2
Q

Definition for gastroenteritis?

A

A common acute communicable intestinal infection causing vomiting, fever and diarrhoea

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3
Q

Definition of acute diarrhoea?

A

3 or more loose stools / 24 hours for < 14 days

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4
Q

Describe epidemiology of rotavirus gastroenteritis?

A
  • Each year, in children < 5 yrs in Australia
    • 115,000 visit GP
    • 22,000 go to ED
    • 10,000 admitted (3,700 in NSW)
    • 1 death (may be underestimate)
  • Rotavirus was responsible for 50% of gastro admissions
  • First infection age 3-36 months likely most severe
  • Peak in mid to late winter
  • Indigenous kids x 3-5 admission, ALOS 5 v 2 days
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5
Q

Causes of gastroenteritis?

A
  • Viruses (70%)
    • Rotavirus
    • Adenovirus
      • Epidemics, rash maybe prominent
    • Norovirus (Calicivirus)
      • Epidemics - camps, schools, child care Game of Thrones (Khaleesi-virus, get it?)
    • Others
      • Enteroviruses
      • Parechovirus
      • Astrovirus
  • Bacteria (15%)
    • Campylobacter
    • Salmonella
    • E.coli
      • enteropathogenic, enterotoxigenic
    • Others
      • Shigella
      • S Typhi
      • Cholera
      • Yersinia (reputation for mimicking appendicitis)
  • Parasites
    • Giardia
    • Cryptosporidium
    • Others: entamoeba
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6
Q

Describe rotavirus (pathophys, transmission, complications).

A
  • RNA virus (family Reoviridae)
    • many serotypes/genotypes
    • immunity not life-long
    • vaccine available free since July 2007
    • 80-100% of > 3 yo have antibodies
    • incubation 1-3 days → vomiting
    • temp > 39C in 1/3
  • Faecal – oral transmission
    • minor resp spread (?important in hospital)
  • • Small bowel damage
    • virus penetrates cells of small bowel
      • villus destruction
      • takes 5-7 days to reform
    • loose watery stools, full of rotavirus
      • nosocomial infection very common – profuse early vomiting
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7
Q

Describe human parechovirus (presentation, complications, investigation, management)

A
  • Can cause acute sepsis-like syndrome with fever >38C in infants <3months, followed by erythematous rash
  • Presentation + acute sepsis-like syndrome + fever
    • Irritability and appearing to be in pain
    • Maculopapular or erythematous rash
    • Distended abdomen, diarrhoea
    • Tachycardia
    • Tachypnoea
    • Encephalitis
    • Myoclonic jerks
    • Hepatitis
  • Complications
    • Volvulus
    • Intussusception
    • Bowel ischaemia
  • Investigation: stool culture
  • Management: supportive care
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8
Q

Describe campylobacter (source, clinical presentation)

A
  • wide variety animal hosts, incl chicken
  • abdo pain maybe prominent
  • maybe difficult to find in outside labs
  • findings on laparotomy
    • ileum inflamed, oedematous
    • mesenteric adenitis
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9
Q

Describe salmonella (source, pathophys)

A
  • contaminated food, summer epidemics
  • mucosal invasion, colitis prominent
  • white cells in stool
  • prolonged excretion of salmonella
    • age 3 months: 27% at 8/52, 8% at 6/12
    • older kids: 7% at 8/52, 2% at 6/12
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10
Q

Describe diagnosis of gastroenteritis?

A
  • Diagnosis of GE in children usually made on basis of history, examination and awareness of epidemiological information
  • Investigations (blood, stool, urine, other) may be needed to rule out conditions other than GE, or to inform management decisions (degree of dehydration etc)
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11
Q

Factors supporting cause of gastroenteritis: viral vs bacterial?

A
  • Viral / Rotavirus
    • Presents in autumn/winter
    • Watery diarrhoea without blood
    • +/- vomiting
    • Low grade fever
    • Anorexia
    • 90% under 5 years
  • Bacteria
    • Blood and mucus in stool
    • +/- vomiting
    • High fever
    • May have history of recent travel
    • May be food borne
    • Haemolytic uraemic syndrome - ARF, thrombocytopaenia, microangiopathic haemolytic anaemia
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12
Q

Important aspects on history for the vomiting child?

A
  • Vomiting - how frequent, bile, blood
  • Stool output - number of stools, blood, mucous, watery
  • Intake (compare to usual – is it at least 50%)
    • how much, type of fluid (e.g. water, juice, ORS)
  • Urine output (compare to usual – is it at least 50%)
    • number of wet nappies
  • Lethargy, drowsy, colour, abdo pain, rash, bruise
  • Other changes
  • Duration of illness
  • Loss of weight (Blue Book – Personal Health Record)
  • Other family members ill
  • Previous illness (e.g. short gut)
  • Family history (e.g. inflammatory bowel disease)
  • NB: Age of child:highest risk in young infants
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13
Q

Important aspects on examination for the vomiting child?

A
  • Initial impression – “gestalt”
    • Stop. Take some time to look, listen, smell…
  • Centiles
    • Is there a pre-existing growth problem? Use charts.
  • Assess hydration
  • System exam – Head to toe starting with GIT…
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14
Q

Differentials for the vomiting child/gastroenteritis?

A
  • Gastroenteritis: triad of fever, vomiting, diarrhoea
  • Acute appendicitis
  • Strangulated hernia
  • Intussusception of other causes of bowel obstruction
  • Urinary tract infection
  • Meningitis and other types of sepsis
  • Any cause of raised intracranial pressure
  • Diabetic ketoacidosis
  • Inborn errors of metabolism
  • Inflammatory bowel disease
  • Haemolytic uraemic syndrome
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15
Q

What red flags are there with vomiting/when to consider another differential other than gastroenteritis?

A
  • Blood in the stool or vomit
    • bloody stool: intussesception
    • bloody vomit: mallory weiss tear, sepsis
  • Bile in vomit - bowel obstruction, intussusception, malrotation
  • Vomiting but no diarrhoea - bowel obstruction, intussusception, malrotation
  • Diarrhoea first, then vomiting - unusual, appendicitis, bowel obstruction
  • Headache - raised ICP, meningitis, significant ear infection
  • Very high fever (>39C) - other infectious causes
  • Young child (esp < 3m) - other infectious causes
  • Severe abdominal pain / distension - acute abdomen
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16
Q

What investigations to consider with gastroenteritis/vomiting in children?

A
  • In mild cases no blood or other tests are required
  • In moderate to severe dehydration consider
    • Electrolytes, urea and creatinine, BGL
      • * EUC essential in any child having IV fluid
    • Full blood count
    • Stool micro, culture, virology
  • If considering other aetiology
    • Urine micro & culture
    • Blood culture (if temp >38.5°C)
    • X-ray: AXR, CXR, ultrasound, air enea
17
Q

What is the initial management for vomiting in children/gastroenteritis?

A
  • Initial management is always
    • A Airway
    • B Breathing
    • C Circulation
    • DEFG Don’t Ever Forget Glucose
18
Q

Describe the management algorithm for acute gastroenteritis in children

A

19
Q

Is there a benefit in having sodium and glucose in oral rehydration therapy?

A
  • Yes. Effectiveness proven >30 years ago
  • 1960s: intestinal water absorption mediated by active transport
    • sodium and glucose co-transported equi-molar ratio
    • ie when one molecule of glucose is absorbed, it takes a friend (Na)
    • – 2% - 4% glucose gives max absorption
  • Co-transporter continues to function in cholera
  • Does not reduce stool volume or duration of diarrhoea
  • Children may continue to vomit, while having ORS
20
Q

Describe the composition of different oral rehydration solutions

A
21
Q

When to refer gastroenteritis for admission?

A
  • Severe dehydration
  • At risk of dehydration (age < 6mths, high frequency of watery stools or vomits, minimal oral intake, worsening symptoms)
  • High risk of complications (diabetes, renal failure, poor nutrition)
  • Diagnosis in doubt or surgical diagnosis considered
  • Parent or carer unable to manage at home
  • Unsuccessful at oral rehydration
22
Q

When do you reassess after initial management for gastroenteritis?

A
  • It is expected that the child who is receiving rehydration therapy should continue to improve over the next 6 to 8 hours
  • If not improving then think again or CONSULT
  • If improving then COMMENCE ORAL INTAKE (ie early, with hunger)
23
Q

What are the advantages of early re-introduction of food?

A
  • Early re-feeding associated with nutritional advantages
  • Continue breast feeding throughout illness
  • Enhance enterocyte regeneration
  • Recovery of brush border membrane disaccharidases
  • No advantage to re-grading feeds
24
Q

What do you NOT do with acute gastroenteritis to prevent it from becoming chronic?

A
  • Restrict dietary intake
    • Delay feed reintroduction
    • Elimination diets
  • Give high volume juices, cordials etc
    • Apple juice the worst culprit
  • Use antibiotics
  • Use antidiarrhoeals
25
Q

Is there any benefit with lactose free feeds in gastroenteritis?

A

Routine use of lactose-free feeds is not recommended. Use if reducing substances in stool and diarrhoea prolonged.

26
Q

Describe the rotavirus vaccine

A
  • Rotarix (NSW, ACT)
    • No. of doses: 2
    • Ages: 2m, 4m
    • Vol/dose: 1mL
  • Oral live attenuated vaccines
  • Reduces risk of severe rotavirus GE by 85-100%, risk of any rotavirus GE by ~ 70%
  • Sl increased risk of intussusception
27
Q
A