Volumes and Ventilation- Lecture 2 Flashcards

1
Q

Minute Ventilation

A

VE= VT * f

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2
Q

P

B

A

Barometric pressure

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3
Q

P

PL

A

Pleural pressure

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4
Q

P

A

A

Alveolar pressure

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5
Q

Collapsing forces of the lungs

A

Surface tension.

Lung elastic recoil.

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6
Q

Compliance

A

= delta V (mL) / delta P (cmH2O)

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7
Q

Breath

A

Defined as an inspiration and the subsequent expiration.

2 phase: inflation and deflation phase.

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8
Q

Airflow is zero when…

A

At the beginning of a breath and when the inspiration is complete.

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9
Q

Laplace law

A

P = 2τ/r
When radius decreases the increase required to keep bubble open particularly important with microscopic alveoli, need to reduce τ to minimize P and prevent alveolar collapse.

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10
Q

Alveolar type II cells

A

Produce surfactant.

Surfactant reduces surface tension between the watery substance around it to prevent collapse

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11
Q

Surfactant

A

(water/oil barrier) Reduces surface tension between the watery substance around the alveolar cell to prevent collapse and transudation. Lose of surfactant can lead to lung collapse and edema.

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