Volumes and Ventilation- Lecture 2 Flashcards
Minute Ventilation
VE= VT * f
P
B
Barometric pressure
P
PL
Pleural pressure
P
A
Alveolar pressure
Collapsing forces of the lungs
Surface tension.
Lung elastic recoil.
Compliance
= delta V (mL) / delta P (cmH2O)
Breath
Defined as an inspiration and the subsequent expiration.
2 phase: inflation and deflation phase.
Airflow is zero when…
At the beginning of a breath and when the inspiration is complete.
Laplace law
P = 2τ/r
When radius decreases the increase required to keep bubble open particularly important with microscopic alveoli, need to reduce τ to minimize P and prevent alveolar collapse.
Alveolar type II cells
Produce surfactant.
Surfactant reduces surface tension between the watery substance around it to prevent collapse
Surfactant
(water/oil barrier) Reduces surface tension between the watery substance around the alveolar cell to prevent collapse and transudation. Lose of surfactant can lead to lung collapse and edema.