Volatile Anesthetic Flashcards
Nitrous Oxide Saturated Vapor Pressure (mm Hg)?
38,628
Halothane Saturated Vapor Pressure (mm Hg)?
243
Isoflurane Saturated Vapor Pressure (mm Hg)?
239.5
Sevoflurane Saturated Vapor Pressure (mm Hg)?
157
Desflurane Saturated Vapor Pressure (mm Hg)?
669.2
Nitrous Oxide MAC value?
105%
Halothane MAC value?
0.74%
Isoflurane MAC value?
1.15 %
Sevoflurane MAC Value?
2.05%
Desflurane MAC value?
6.0%
Nitrous Oxide Blood/Gas coefficient?
0.47
Halothane Blood/Gas coefficient?
2.3
Isoflurane Blood/Gas coefficient?
1.4
Sevoflurane Blood/Gas coefficient?
0.69
Desflurane Blood/Gas coefficient?
0.42
Nitrous Oxide Brain/Blood, Muscle/Blood, and Fat/Blood coefficients?
BB 1.1
MB 1.2
FB 2.3 (Least soluble/Potent)
Halothane Brain/Blood, Muscle/Blood, and Fat/Blood coefficients?
BB 2.9
MB 3.5
FB 60 (Most potent VA/ most soluble)
Isoflurane Brain/Blood, Muscle/Blood, and Fat/Blood coefficients?
BB 2.6
MB 4.0
FB 45
Sevoflurane Brain/Blood, Muscle/Blood, and Fat/Blood coefficients?
BB 1.7
MB 3.1
FB 48
Desflurane Brain/Blood, Muscle/Blood, and Fat/Blood coefficients?
BB 1.3
MB 2.0
FB 27
What VA is most likely to cause Malignant Hyperthermia?
Halothane
Time Constant = _______/________
capacity of the system/ flow into the system
1 Time constant =
63% change
2 Time constants =
85% change
3 TC =
95% Change
4 TC =
98% Change
equation for Uptake of VA?
Cardiac output X B/G coefficient X ((PA-PV/BP mmHG)
MAC BAR
Blunt Autonomic Responses
30-40% greater than MAC
MAC
ED 50 - 50percent pt wont move to surgical incision
MAC awake
1/3 to 1/4 MAC
What is the last sense lost and first regained during induction and emergence?
Hearing
What percentage of CO do pediatrics’ VRG get when compared to adults?
Kids = 18% —- Adults 6-10% weight
Kids have higher Induction of CO to VRG
Kids = faster induction than adults