vocab Flashcards
sensitivity
likelihood of true positive results w/ the disease. __ of test in proportion of ppl known to have dz who test positive for it. ___= positive in disease. TruePos/total # of ppl w/ dz in pop
specificity
likelihood of a true negative result in those who are healthy (dz free). relates to tests ability to identify negative results ___ test, when positive, helps to rule in disease. __ of a test defined as the proportion of pt’s that are known not to have the dz who will test negative for it. TrueNeg/total # w/o dz (healthy individuals).
Tanner Stage 1 Male
Pre-puberty; asexual
Tanner Stage 2 Male
Testes enlg; scrotal skin reddening w/ change in texture; sparse growth of long, slightly pigmented pubic hair at base of penis.
Tanner Stage 3 Male
inc in penile length but min change in width, sometimes called ‘pencil penis’ stage; further scrotal enlgmnt; pubic hair darker, coarser, covers greater area; onset of growth spurt
Tanner Stage 4 Male
inc in penile length & width w/ development of glans; further darkening of scrotal skin; adult-type pubic hair w/ no spread to medial surface of thighs.
Tanner Stage 5 Male
full adult genitalia; adult type pubic hair w/ spread to medial surface of thighs.
Tanner Stage 1 Female
pre-puberty/ asexual.
Tanner Stage 2 Female
breast buds & papilla elev’d; downy pigmented pubic hair along labia majora.
Tanner Stage 3 Female
breast mound enlgmnt; darker, coarser, curling pubic hair on mons, labia majora; onset of growth spurt.
Tanner Stage 4 Female
Areola & papilla elev’d to form a 2nd mound above level of breast; adult-type pubic hair w/ no spread to medial surface of thighs; menarche.
Tanner Stage 5 Female
Recession of areola to mound of breast, extension of pubic hair to medial thigh.
normal/healthy women of reproductive age
vag pH 3.8-4.2. white, clear, flocculent discharge. absent odor. lactobacilli under microscope. no complaints. no intervention.
Candida vulvovaginitis. candida albicans 80-90%
vag pH usually d. amine odor: usually absent. microscopic: mycelia, budding yeast, pseudo-hyphae w/ KOH prep. complaints: itching/burning, discharge. intervention: -azole antifungal, po (fluconazole/diflucan) or vag clotrimazole/monistat, terconazole.
BV; etiology- unclear, likely polymicrobial assoc’d w/ G. vaginalis, M. hominis.
vag pH >4.5. discharge: thin, homogeneous, white, gray, adherent, often inc’d. amine odor (KOH ‘whiff’ test): present (fishy). microscopic: >20 clue cells/HPF few or no WBCs. complaints: discharge, foul odor, itching occasional. Rx: metronidazole (topical metrogel) or po flagyl, clinda vag cream or ovules (cleocin), po tinidazole.
atrophic vaginitis, etiology- estrogen deficiency
vag pH >5. discharge: scant, white-clear. amine odor: absent. microscopic few or absent lactobacilli. complaints: itching/burning, discharge, but often w/o sx’s. Rx: topical &/or vag estrogen if sx.
genital herpes
common asymp or atypical sx’s. classic presentation: painful ulcerated lesions, lymphadenopathy w/ initial lesions. women- thin vag d/c if lesion located at vagina or introitus. tx- acyclovir, famciclovir, valacyclovir.
nongonococcal urethritis & cervicitis. (chlamydia)
irritative voiding sx’s, occasional mucopurulent dc. women- cervicitis common. often w/o sx’s in either gender. micro exam of dc- lg # of wbc’s. tx: azithro 1 time dose 1st line. alt: doxy, erythro, ofloxacin, levofloxacin (multi days of tx needed). most common bacterial sti
gonococcal urethritis & vaginitis (gonorrhea)
irritative voiding sx’s, occasional purulent dc. often w/o sx’s in either gender. micro exam of dc- lg # of wbc’s. tx: ceftriaxone IM 1 time dose + azithro x1 dose or doxy x7d.
trichomoniasis (t. vaginalis)
dysuria, itching, vulvovaginal irritation, dyspareunia, yellow-green vag dc, occasionally frothy, cervical petechial hemorrhages (strawberry spots). often w/o sx’s in either gender. on micro exam: motile organisms & lg # wbc’s. alkaline pH. tx: po metronidazole or tinidazole 1x dose. avoid alcohol during tx of po metronidazole or tinidazole. abstinence from alcohol cont x24 hr after metro or 72hr after tinidazole.
syphilis (t. pallidum)
primary stage: chancre (firm round, painless genital &/or anal ulcer w/ clean base & indurated margins) accompanied by lymphadenopathy, ~3wks duration, resolve w/o tx. Secondary stage: nonpruritic skin rash, often involving palms & soles, as well as mucous membrane lesions. Fever, lymphadenopathy, sore throat, patchy hair loss, HA’s, wt loss, muscle aches, & fatigue common. resolution w/o tx possible. latent stage: presentation variable occurs when primary & 2ndary sx’s resolve. tx: antimicrobial tx w/ dose & length dictated by stage. options: ink PCN (1st line), tetracycline, or doxy.
Genital warts (condyloma acuminata) HPV 6&11 genital warts. HPV 16, 18, 31, 33 assoc’d w/ GU malignancies.
most common STI. verruca-form lesions can be subclinical or unrecognized. location of lesion can guide choice of tx. podofilox, liquid nitrogen, cryoprobe, trichloracetic acid, podophyllin resin, surgical removal, or imiquimod (only indicated for external warts). trichloroacetic acid & cryoprobe preferred tx during preg.
pelvic infalmm dz- gonorrhea, chlamydia, bacteroides, eneterobacteriaceae, streptococci.
infectious, inflamm d/o of upper female reproductive tract, incl uterus, fallopian tubes, adjacent pelvic structures. ascension of sti. irritative voiding sx’s, fever, abd pain, cervical motion tenderness, vag dc. possible sequela incl tubal scarring w/ subsequent inc’d risk for ectopic preg &/or infertility. tx: ceftriaxone IM 1x dose + doxy x 14d w/ or w/o metronidazole x14d.
epididymitis/ epididymoorchitis. </=35 yrs
upper reproductive tract infection w/ inflamm of epididymis/testis). etiology: N. gonorrhoeae, C. trachomatis. irritative voiding sx’s, fever, & painful swelling of epididymis, & scrotum. infertility potential post infection. pain. tx: ceftriaxone IM 1xdose + doxy x10d (same as women PID). advise scrotal elev to help w/ sx relief. Plehn’s sign= relief of discomfort w/ scrotal elev.
epididymitis/ epididymoorchtis. >/=35 yrs or insertive partner in anal intercourse
enterobacteriaceae (coliforms). irritative voiding sx’s, fever, & painful swelling of epididymis & scrotum. infertility potential post infection. voiding pain. primary tx: cipro qd or levofloxacin qd x 10-14d. plehn’s sign doesn’t apply.
acute bacterial prostatitis, </= 35 yrs
etiology: gon & chlamydia. irritative voiding sx’s, suprapubic, perineal pain, fever, tender, boggy prostate, leukocytosis. tx: ceftriaxone IM x1dose, then doxy bid x10d.
acute bacterial prostatitis >35 yrs
etiology: enterobacteriaceae (coliforms). irritative voiding sx’s, suprapubic, perineal pain, fever, a tender, boggy prostate, leukocytosis. tx: cipro or ofloxacin x14d.
paraphimosis
retracted foreskin that cannot be brought forward to cover the glans
varicocele
a palpable, ‘nest of worms’ scrotal mass that is only evident in standing position
hydrocele
collection of serous fluid that causes painless scrotal swelling, easily recognized by transillumination
phimosis
w/ this, the foreskin cannot be pulled back to expose the glans
testicular torsion
characterized by scrotal pain & loss of the cremasteric reflex
cryptorchidism
testicle located in inguinal canal or abdomen
cholinesterase inhibitors= donepezil (aricept), rivastigmine (exelon), galatamine (razadyne)
mild-mod stage dz, considered to be mainstay of tx. clear tho minor & time-ltd benefits by inching availability of acetylcholine. AE: GI effects. more acetylcholine in body- cholinergic SEs: salivation, ^GI motility, lacrimation, urination, defecation, bradycardic.
N-methyl-D-aspartate receptor antagonist= memantine (Namenda).
protects neurons that make acetylcholine. tx of mod-severe AD. thru its effect on glutamate, helps create an environment that allows for storage & retrieval of info.
lumbar spinal stenosis
older age >/=50; standing discomfort w/ improvement in sx’s w/ bending forward; pseudoclaudication; bilateral lower extremity numbness, weakness in majority. dx: initially none indicated. for sx’s >1mo, consider MRI, EMG/NCV. intervention: physical tx, NSAIDs, epidural corticosteroid inj, perhaps surgery.
stress incontinence
assoc’d w/ lifting
transient incontinence
occurs during an acute illness
urge incontinence
reports of strong sensation of needing to void
functional incontinence
often occurs in presence of mobility problems
McMurray test
meniscal tear
talar tilt
ankle instability
tinel’s sign
carpal tunnel syndrome