Vitamins Uses Flashcards
Vitamin A (Name)
Retinol
Vitamin B1 (Name)
Thiamine
RDA
Recommended Dietary Allowance
Average intake lvl to meet needs of 97.5% of health ppl
AI
Adequate intake
Average Intake lvl assumed to be adequate based on observations or experiments
UL
Tolerable Upper Intake Lvl
Highest intake lvl likely to pose no adverse effects to almost all ppl
Vitamin B2 (Name)
Riboflavin
Vitamin B3 (Name)
Niacin
Vitamin B6 (Name)
Pyridoxine
Vitamin B9 (Name)
Folate (Folic Acid)
Vitamin B12 (Name)
Cyanocobalamin
Vitamin C (Name)
Ascorbic Acid
Vitamin D (Name)
Ergocalciferol
Vitamin E (Name)
Alpha-tocopherol
*Fat Soluble
Vitamin K (Name)
Phytonadione
Ca (Name)
Calcium
Fe (Name)
Iron
Mg (Name)
Magnesium
Zn (Name)
Zinc
Vitamin A (Use)
Eye Sight (AMD + Cataracts)
Fat Soluble
Vitamin A (Dosing)
UL: 3000 mcg of preformed VITAMIN A
1 mcg RAE = 1 mcg Retinol
Vitamin A (Adverse effects, CI, etc)
- Hepatotoxicity*
- Retinol can cause birth defects by preg women*
careful taking retinol med and supplement together
Vitamin C (Use)
Wound Healing
Absorption of iron
Immune function
Vitamin C (Dosing)
RDA = 75-90 mg/day
UL = 2g/day
200mg vit C for every 30mg of iron
Vitamin C (Adverse effects, CI, etc)
Kidney stones dose 1g/day due to water solubility
Diarrhea,Nausea, Abdominal cramps, Heartburn
Vitamin B2 (Use)
Cataracts and Migraines
Vitamin B2 (Dosing)
5-30mg daily for cataracts
400mg daily for migraines
Vitamin B2 (Adverse effects, CI, etc)
Generally well tolerated
Diarrhea at large doses (Migraine dose)
Vitamin B3 (Use)
Increase HDL
Lower TG and LDL
Vitamin B3 (Dosing)
1-3g for cholesterol treatment
Vitamin B3 (Adverse effects, CI, etc)
Flushing, Itching, Headache at ~ 50mg/Daily
Hepatotoxicity and Glucose intolerance above 1.5g Daily
not used due to side effects
Vitamin B6 (Use)
Pregnancy Induced nausea and vomiting
Vitamin B6 (Dosing)
dosed at 10-25mg TID or QID for Pregnancy N/V
Vitamin B6 (Adverse effects, CI, etc)
Sensory neuropathy, keep daily dose below 200mg
Vitamin B9 (Use)
Prevention of neural tube defects (dose 400mcg/day)
Alcohol Dependency
Can reduce side effects of low dose methotrexate used for RA
Vitamin B9 (Dosing)
400 mcg adults, 600 mcg during pregnancy
Vitamin B9 (Adverse effects, CI, etc)
Can mask pernicious anemia
Can reduce efficacy of methotrexate when used in cancer
Anti epileptics reduce folate levels
Vitamin B12 (Dosing)
Treatment dose is >100mcg, used to be given IM but PO is easier and is equivalent to most people
Technically Im absorbed better
Vitamin B1 (Use)
Thiamin Deficiencies
Caused by Alcohol dependence, increased risk of Wernickes encephalopathy
Vitamin B1 (Dosing)
RDA = 1.1mg
Supplement 1-2mg
Treatment = 10-300mg
Vitamin B1 (Adverse effects, CI, etc)
Well tolerated
Vitamin D (Use)
Bone Health (Osteoporosis & Fall Prevention)
Fat Soluble
Vitamin D (Adverse effects, CI, etc)
Hypercalcemia
increased Vitamin D leads to increased calcium absorption. potential calcium buildup heart
Consider sun time/skin color/sunscreen. ppl may require more than RDA
Vitamin E (Use)
Possibly effective…
Dementia and Age-related macular degeneration
Vitamin E (Dosing)
2000IU/Day for dementia
400 IU/Day for AMD
Vitamin E (Adverse effects, CI, etc)
Increased risk of mortality in dose >400IU daily for those with co-morbidities/CVD/old
Bleeding risk >400 IU Daily
Vitamin K (Use)
Reverse Warfarin
*Fat Soluble
Vitamin K (Dosing)
2.5-5mg for warfarin reversal
Vitamin K (Adverse effects, CI, etc)
found in leafy veggies
Calcium (Use)
Osteoporosis
Antacid
Calcium (Dosing)
1000mg/Day (Adult 20-50, men 51-70)
1200mg/day (women >50, men >70)
Calcium (Adverse effects, CI, etc)
Absorption saturated at doses > 500mg, so separate if larger
Calcium carbonate highest % elemental and cheapest
other forms lover % and more $$
Iron (Use)
Iron Deficiency Anemia
Iron (Dosing)
For anemia: 100-200mg elemental iron divided into a few doses due to causing GI upset + poorly tolerated
Iron (Adverse effects, CI, etc)
Nausea/Vomiting
Constipation
Abdominal Pain
Dark Poop
Magnesium (Use)
Constipation
Headaches
Magnesium (Adverse effects, CI, etc)
Diarrhea
Chronic PPIs and Diuretics and decrease magnesium
Zinc (Use)
Common Cold
Wound Healing
AMD
Zinc (Dosing)
.
Zinc (Adverse effects, CI, etc)
Metallic taste, Nausea and vomiting
Avoid intranasal gel/sprays (anosmia - loss of smell)
Separate antibiotics by 3 hrs
EAR
Estimated Average Requirement
Avg intake lvl estimated to meet req of half the health ppl
1 mcg cholecalciferol =
40 IU Vitamin D
Vitamin C for colds info
doesn’t decrease risk of catching unless chronic smoker/elderly
Taking after onset of symptoms no benefit
Prophylactic may decrease duration by 1/1.5 days
Dose: 2g better than 1g but 3g useless
Vitamin D2 is
ergocalciferol
Vitamin D3 is
cholecalciferol
more potent
Vitamin D monitoring…
Deficient = <12 ng/ml Insufficient = 12-20 ng/ml Goal = 30-60ng/ml
Expensive to regularly have done
What Decreases absorption Iron
Antacids
H2 blockers
PPIs
Calcium, Coffee + Tea
Iron interferes with absorption of…
Bisphosphonates
Levothyroxine
Fluoroquinolone
Tetracycline
Either separate or discontinue when taking antibiotics
What increase absorption iron
Vitamin C
When should infants receive vitamin D supplement?
only if breastfeed, formula already contains vitamin D
Vitamin D Dosing for 0-12 months
400IU or 10 mcg
Vitamin D Dosing for 1-70y
600IU or 15 mcg
Vitamin D dosing for >70y
800IU or 20 mcg (UL = 4000 IU or 100mcg)
High doses of beta-carotene can lead to…..
skin turning yellow, harmless and it goes away
When labels calculate total vitamin A they can….
combine retinol and beta-carotene into a single amount.
ex. Contains 4000mg vitamin A, 2000mg beta-carotene then assume 2000mg retinol or preformed
What is Preformed Vitamin A
active form
Meat, poultry, dairy products, retinol
What is Provitamin Vitamin A
not activated yet
Fruits/Veggies
Beta-carotene
Ferrous sulfate is…
most common iron
325mg is 65mg elemental
Vitamin B6 Interactions
Decreases Folic Acid Concentrations
Anti-epileptics may decrease B6
B12 Deficiency is common in….
older adults
Pernicious anemia
strict vegetarians
B12 Interactions
Acid suppression will decrease absorption (PPIs, H2R blockers)
Metformin will decrease levels
When should B12 levels be checked for those taking metformin?
After 1 year on it
Which form of calcium will have absorption affected by PPIs and is acid dependent?
Calcium Carbonate