Vitamins / Minerals Flashcards
vitamins
organic compounds needed to support metabolism. do NOT supply energy. C skeleton source. Essential except for D, K and A.
Fat soluble Vitamins
A, K, E, D
Water soluble vitamins
C and B complex
Vit. A forms and functions
Retinol and Carotenes. Fxns: vision derm: epithelial health, mucus production, antibacterial and anti inflammatory transcription: regulates Growth, devpt, reproduction
sources of vit. A
animal fats, green and orange veggies
Vit. A deficiency (most prominent vit. deficiency in the world)
Nyctalopia: night blindness due to role in phototransduction
Xerophthalmia and keratomalacia: dryness of tissues due to epithelial health role
complete blindness
Vit. D (D3) cholecalciferol fxns
maintenance of blood Ca levels.
fxns w/ PTH to increase: absoprtion from small intestine, renal absorbption and liberation from bone by osteoclasts.
sources of vit. D
fatty fish and forified diary products
Vit. D deficiency
Decreased bone mineralization
Rickets in children - enlarged head, rib cage, pelvis, joints, leg deformity,
Osteomalacia in adults - weakened bones, deformity, fxs
Poor muscle tone, restlessness and irritability
Vit. E (tocopherol) fxns and sources
Fxn: antioxidant: radical scavenger, protects cell membranes and lipids, plays role in eye and neuro fxns, inhibits platlet coag.
Vit. E Deficiency / toxicity
def: rare, possible anema
tox: associated risk of vit. K def. and decreased clotting/slow wound healing
Vit. K fxn
carboxylation of glu residues (Gla) which is involved in Ca binding, blood coagulation, bone metabolism and vascular biology.
Vit. K drug intercation
can reverse anticog activity of Warfarin
Vit. K def.
decrased coag. anemia. bleeing bruising etc.
water soluable vitamins
dissolve in water; (C and B) b comples are cofactors and enzymes for energy production
B1 fxn
thaimine.
Es: TPP = coenzyme in energy provision
B1 deficiencies
thiamine Beri Beri: neuro and cardio disease optic neuropathy: vision loss aclocholic brain dieses wernickes encephalopathy: most freuqent Korsakoff's syndrome:
B2
riboflavin