Vitamins Flashcards
Casmir Funk
Coined term vitamines in 1911
Named thiamine go reflect belief all vitamins contained nitrogen, which then was wrong - vitamines changed to vitamins
Vitamers
Different chemical forms of each vitamins
Generally similar in structure
Key functions of vitamins
Immune system support
Regulating gene expression
Supporting neurological activity
Facilitating ATP production
Manufacturing blood cells
Regulation of hormones
Vitamins
Carbon containing compounds
Absorbed in small intestine
Essential for normal growth and functioning
Some vitamins produced by intestinal bacteria
Vitamin dependent enzymes
Required for activation of vitamin dependent enzymes (ie cofactors)
Eg B vits vital cofactor for action of CYP450 enzyme system, needed for phase 1 detox
2 types of vitamins
Fat soluble
Absorbed with fat in small intestine into lymphatic capillaries and then into blood
Readily stored
Tighter range between efficacy and toxicity than water soluble
Water soluble
Absorbed into small intestine directly into blood
Storage is minimal (except B12) and easily excreted in excess
Vitamin insufficiency to deficiency
- Preliminary reduction of stores
- Reduction of enzyme activity (infections, frequent herpes outbreak, low sleep, slow healing, cold dragging on)
- Physiological impairment (more prone to infection, poor concentration, sleep issues, difficulty coping with stress, mouth ulcers, increased inflammation)
- Classical deficiency symptoms (depression, mental health issues, chronic increase inflammation)
- Terminal tissue pathology (body breaks down, no resilience, life ending)
True deficiency rate (except B12 & D). Most cases are insufficiency
Provitamins
Substance that can be converted into a vitamin
Pre-formed vitamin
Vitamin already formed