VITAMIN C B12 FOLIC ACID

Question 1

two types of vitamin c

Answer 1

ascorbic acid- e300

or ascorbate salts (e301/2/3)

Question 2

sources of vitamin c

Answer 2

fruit and veg and liver

Question 3

function of vitamin c

Answer 3

1. antioxidant
2. required for synthesis of biomolecules(esp collagen)
3. required for iron adsorption

Question 4

definicency diseases of vitamin c

Answer 4

• scurvy
• tooth loss
• Superficial bleeding
• Fragility of blood vessels
• Poor healing
• Compromised immunity
• Mild anaemia (due to reduced iron absorption)

Question 5

vitamin c and collagen synthesis

Answer 5

vitamin c is an anti oxidant that prevents oxidation of fe2+ –> fe 3+

• fe 2+ needed for hydroxlase enzymes
• these enzymes need to hydroxlate proline and lysine to hydroxyproline and hydroxylysine which improves the hydrogen bonding between structures

Question 6

without hydoxylation of proline and lysine what happens

Answer 6

resulting tissue is fragile as the molecules cant H bond properly so SCURVY

Question 7

which tissues are affected by lack of vitamin c

Answer 7

tissues with high turnover i.e PDL

Question 8

how does scurvy manifest?

Answer 8

initial gingival inflammation–> impaired wound healing, bleeding gingival, tooth looseness and damage to PDL

Question 9

who is most at scurvy risk these days

Answer 9

• elderly
• alcohol/drug user
• followers of fad diets
• smokers or exposed to secind hand smoking
• renal faiulure and dilaysis
• malabsorption conditions

Question 10

excess vitamin c = problem?

Answer 10

no as excess will be removed through urine but excess chewable vitamin c can be harmful to enamel as its acidic

Question 11

solution to excess chewable vitamin c tablet problem

Answer 11

check ph when buy

- absorbate or with buffer not pure absorbic acid