Vitamin B12 (cyanocabalamin)

Question 1

used for

Answer 1

to treat deficiency due to anemia, GI pathology, tapeworms, surgery

Question 2

deficiency syndrome

Answer 2

pernicious anemia and megaloblastic anemia: lack of intestinal factor needed to absorb vitamin B12 from food. Supplement must be given as an injection monthly for life

Question 3

essential for

Answer 3

cell reproduction and maturation of RBCs, synthesis of DNA and maintenance of myelin sheath

Question 4

pregnancy category

Answer 4

A but C if parenteral

Question 5

contraindicated

Answer 5

in patients w/ sensitivity to vitamin B12 or other cobalims

Question 6

caution

Answer 6

in patient w/ heart disease, anemia or pulmonary disease

Question 7

drug interactions

Answer 7

alcohol, neomycin-decreased absorption

Question 8

adverse effects

Answer 8

facial swelling
diarrhea
itching
rash

Question 9

serious adverse effects

Answer 9

anaphylactic shock
pulmonary edema
heart failure
sudden death
optic nerve atrophy

Question 10

responsibilities

Answer 10

educate patients that treatment for pernicous anemia will be life long
assess for alcohol use, malabsorption syndromes