Vitamin B1 Thiamine

Question 1

What is the name of vitamin b1

Answer 1

thiamine

Question 2

what is the cofactor of thiamine b1

Answer 2

thiamine pyrophosphate TPP

Question 3

What is the disease caused by deficiency of thiamine b1

Answer 3

beriberi and it effects the peripheral nervous system and =/or or the cardiovascular system system

Question 4

what are the dietary sources of thiamine b1

Answer 4

1 yeast
2 unpolished rice
3 potatoes
4 meat
5 whole grains
6 nuts

Question 5

what is the primary function of thiamine

Answer 5

is a coenzyme in energy producing reactions especially in carbohydrate metabolism

Question 6

how is TPP involved in the oxidative decarboxylation of a keto acids

Answer 6

• pyruvate dehydrogenase
• a-ketoglutrate dehydrogenase
• transketolase in PPP

Question 7

How is TPP located in the peripheral nervous membranes?

Answer 7

responsible for acytl choline synthesis and phosphorylation of sodium transport channel

Question 8

what happens when thiamine is diffecient?

Answer 8

pyruvate accumulates and PPP stops
no energy and no NADPH
since TPP is used in neurotransmission symptoms in nervous system occurs

Question 9

what are the symptoms of thiamine deficiency?

Answer 9

1 loss of apetite
2 constipation
3 nausea
4 depression
5 peripherc neuropathy
6 irritability
7 mental convulaion
8 ataxia
9 opthalmoglegia
10 Wernicke-Korsakoff in chronic alcoholics
this situation