Viruses: Systems Flashcards
0
Q
Enteric Viruses
A
Rotavirus dsRNA (most common, segmented)
Norovirus- ssRNA, shellfish! Vomiting! (Closed setting, ship, plane, picnic)
Polio- GI, paralysis
Coxsackie- oral lesions, HFMD
Enterovirus 70- conjunctivitis
Enterovirus 71- HFMD, paralysis
Astrovirus- ssRNA similar to rotavirus
1
Q
Respiratory viruses
A
Parainfluenza- croup, bronchiolitis, pneumonitis RSV- LRIs in babies, URIs adults Rhinovirus- Fall and Spring Coronavirus & SARS- Winter Influenza- Winter Adenovirus- conjunctivitis
2
Q
Transmissible Spongiform Encephalitis (TSE)
A
Bovine SE- sheep/cattle -> food contamination
vCJD- cattle -> human => MadCow
Kuru- cannibalism
3
Q
Prion MOA
A
Mutant PrP triggers conformational change in normal PrP leading to accumulation and aggregation of mutant (extensive B-sheet formation)
