Viruses lecture 1 Flashcards
How are viruses classified?
according to their genome (single stranded/double stranded, RNA/DNA, sense/antisense)
What is the role of the virus protein capsid?
to protect the genome
Where does the virus life cycle occur?
inside the host cell
Define virus
obligate intracellular parasite
What are the seven viral groups?
- dsDNA viruses
- ssDNA viruses
- dsRNA viruses
- (+)sense RNA viruses
- (-)sense RNA viruses
- RNA reverse transcribing viruses HIV
- DNA reverse transcribing viruses
Name all the DNA virus families (HHAPPPy)
Hepadna Herpes Adeno Pox Parvo Papova
Which DNA viruses have naked capsids?
Dina gets naked for her PAP smear
- parvovirus
- adenovirus
- papovirus
What are virons?
very small rod-like RNA molecules, only plant pathogens (CONTAIN NO PROTEIN)
What are prions?
contain no NUCLEIC ACID
- resistant to heat inactivation
- resistant to radiation damage
- resistant tp DNAase and RNAase Treatment
- sensitive to urea, SDS, phenol and other protein denaturing chemicals
What are the different types of capsid?
- helical
- icosahedral
What are the four steps of virus replication?
- entry
- replication
- assembly
- release
How do viruses attach to the cell?
via receptors called attachment proteins
What determines the outcome of infections?
the interaction of the outer surface of a virus with a cellular receptor
Where do most DNA viruses replicate?
nucleus
Where do most RNA viruses replicate?
cytoplasm
