Viruses/Fungi/Protozoa (Based on Erin's SI Notes) Flashcards
1
Q
Steps of Replicative Cycle
A
- Attachment to cell receptors
- Endocytosis into cell
- Uncoating (liberate protein and DNA/RNA)
- Replication
- -Trascription in nucleus, translation in cytoplasm, make +mRNA from -DNA or -mRNA
- Assembly
- Egress outside cell
2
Q
DNA Viruses
A
- Orthopoxvirus (Variola, small pox)
- Molluscum contagiosum (most common viral skin infection)
- Herpes viridae
- Adenovirus (respiratory infections, conjunctivitis)
- Polymavirus
- Papillomaviridae (HPV, genital warts)
- Anellovirus
- Parvovirus (Fifth’s Disease/slap face skin disease)
- Orthohepadnavirus (Hep B)
3
Q
Herpes viridae family
A
- Herpes simplex 1 (oral herpes, eye infections)
- Herpes simplex 2 (genital herpes)
- Varicella zoster (chicken pox)
- Epstein barr (mono)
- Cytomegalovirus (retinitis/betaherpesvirinae/usualy in immunocompromised)
- HHV6 (roseolavirus)
- HHV8 (kaposi’s sarcoma)
4
Q
RNA Viruses
A
- Hantaan virus
- Rotavirus
- Lyssavirus (rabies)
- Filovirus (ebola)
- Paramyxovirus (Newcastle disease)
- Vesiculovirus (VSV)
- Parainfluenza
- Rubulavirus (mumps)
- Morbillivirus (measles)
- Influenza A/B
- Arenaviridae (lassa fever virus)
- Hepatovirus (Hep A)
- Hep D
- Hep E
- Enterovirus (Polio)
- Rhinovirus (common cold)
- Pneumovirus (respiratory syncytial virus in children/RSV)
- Astrovirus (GI)
- Norwalk (major cause of GI food borne disease)
- Coronavirus (respiratory)
- Flaviviridae (yellow fever/Hep C)
- Togaviridae (Easter equine encephalitis/alpha virus//Rubivirus (rubella)
5
Q
Viruses with Vaccines
A
- Hepatovirus (Hep A)
- Enterovirus (poliovirus)
- Flaviviridae (dengue/yellow fever)
- Eastern equine encephalitis virus (alpha virus)
- Ribivirus (Rubella)
- Rotavirus
- Influenza A/B
- Lyssavirus (Rabies)
- Morbillivirus (measles)
- Rubulavirus (mumps)
- Hep B
- Papillomavirus (HPV)
- Varicella zoster
- Orthopoxvirus (variola smallpox)
6
Q
3 major viruses that cause disease in the US that don’t have a vaccine
A
- Norwalk
- rhinovirus
- RSV
7
Q
Fungal infections of cutaneous layer
A
“TEM” (Trichophyton, Epidermiphyton, Microsporum)
- tinea capitis
- tinea corporis
- tinea cruris
- tinea pedia
- onychomycosis (nail infection)
8
Q
Fungal systemic infection of immunocompetent
A
- Blastomyces
- Coccidioides
- Histoplasma
9
Q
Fungal systemic infection of immunocompromised
A
- Aspergillus
- Cryptococcus
10
Q
Protozoa that cause diarrhea
A
- Giardia
- Isospora
- Sarcocystis
- Cryptosporidium
- Toxoplasma
- Enterocytozoon
- Entamoeba
11
Q
Likely protozoan infections of immunocompromised
A
“TIC”
- Toxoplasma
- Isospora
- Cryptosporidium
12
Q
Common protozoan infections in the US
A
“GET”
- Giardia
- Entamoeba
- Trichomonas vaginalis
13
Q
Protozoal cysts
A
- Giardia
- Entamoeba
- Toxoplasma (found in cat litter boxes)
14
Q
Bugs that cross placental membrane
A
“ToRCHeS”
- Toxoplasma
- Rubella
- Cytomegalovirus
- Herpes/HSV/HIV
- Syphilis
15
Q
Bugs treated with Bactrim
A
- Cryptosporidium
- Isospora
- PCP
