Viruses Flashcards
HIV investigation x2?
Retrovirus
Western blotting
HIV complication?
AIDS
AIDS can be classed if….?
CD4<200 and AIDS defining illness
HIV/AIDS treatment?
Anti-retroviral HAART
Herpes simplex investigation?
Inclusion bodies
Herpes simplex x2 pathologies?
Cold sores
Genital ulcers and dysuria
Herpes simplex virus treatment?
Acyclovir
Herpes varicella zoster investigation?
ELISA - IgM antibody
Herpes varicella zoster x2 pathologies?
Chicken pox
Shingles
Herpes varicella zoster treatment for children and adults
Children - calamine
Adults - acyclovir
Immunocompromise - VZV immunoglobulin
EBV investigation?
Immunofluorescent anti-IgG
EBV pathology?
Glandular fever
EBV treatment?
None
Human papilloma virus pathology and treatment?
Genital warts with surgery/cauterization
Cytomegalovirus investigation?
Owl eye inclusion bodies
CMV pathology?
Also consider immunocompromised
Glandular fever-like
Immunocompromised - pneumonitis/hepatitis/diarrhoea
Hepatitis B investigation?
DNA and ELISA
Hepatitis A from which fish?
Shellfish
Hepatitis B will cause?
Fever/malaise/arthralgia/jaundice/pruritus
Hepatitis B treatment?
Manage as chronic
Hepatitis C investigation?
PCR - Hep C RNA
Hepatitis C from?
Intravenous drug user (IVDU), blood, sex
Hepatitis C causes?
Mild can get cirrhosis
Hepatitis C treatment?
Manage as chronic
Hepatitis A investigation?
ELISA - IgM antibody positive
Hepatitis A causes?
Fever/malaise/arthralgia/jaundice/rigor
Hepatitis A treatment?
Supportive
Influenza A/B investigation? x2 (not that important)
RNA
NAAT/complement fixation
Influenza A/B causes?
Fever/malaise/arthralgia
Influenza A/B treatment?
Supportive
Flu vaccine
Respiratory Syncytial Virus causes?
Bronchiolitis (infants)
Croup
Morbillivirus investigation x2?
Inclusion bodies
IgM +ve
Morbillivirus causes?
Measles
Enterovirus causes?
Measles
Enterovirus investigation?
Culture the CSF
Rubivirus causes?
German measles/Rubella
Rubivirus investigation?
Rubella-specific IgM +ve
Rubivirus treatment?
MMR vaccine (prevent), no treatment
Paramyxovirus test?
Salivary IgM +ve
Paramyxovirus causes?
Mumps
Paramyxovirus treatment?
Supportive
Parvovirus investigation?
ELISA - IgM +ve (acute and will produce IgG so long-term protected)
Parvovirus causes?
Slapped cheeks
Parvovirus treatment?
Supportive