Viruses Flashcards

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1
Q

HIV investigation x2?

A

Retrovirus

Western blotting

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2
Q

HIV complication?

A

AIDS

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3
Q

AIDS can be classed if….?

A

CD4<200 and AIDS defining illness

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4
Q

HIV/AIDS treatment?

A

Anti-retroviral HAART

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5
Q

Herpes simplex investigation?

A

Inclusion bodies

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6
Q

Herpes simplex x2 pathologies?

A

Cold sores

Genital ulcers and dysuria

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7
Q

Herpes simplex virus treatment?

A

Acyclovir

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8
Q

Herpes varicella zoster investigation?

A

ELISA - IgM antibody

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9
Q

Herpes varicella zoster x2 pathologies?

A

Chicken pox

Shingles

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10
Q

Herpes varicella zoster treatment for children and adults

A

Children - calamine
Adults - acyclovir
Immunocompromise - VZV immunoglobulin

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11
Q

EBV investigation?

A

Immunofluorescent anti-IgG

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12
Q

EBV pathology?

A

Glandular fever

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13
Q

EBV treatment?

A

None

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14
Q

Human papilloma virus pathology and treatment?

A

Genital warts with surgery/cauterization

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15
Q

Cytomegalovirus investigation?

A

Owl eye inclusion bodies

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16
Q

CMV pathology?

Also consider immunocompromised

A

Glandular fever-like

Immunocompromised - pneumonitis/hepatitis/diarrhoea

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17
Q

Hepatitis B investigation?

A

DNA and ELISA

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18
Q

Hepatitis A from which fish?

A

Shellfish

19
Q

Hepatitis B will cause?

A

Fever/malaise/arthralgia/jaundice/pruritus

20
Q

Hepatitis B treatment?

A

Manage as chronic

21
Q

Hepatitis C investigation?

A

PCR - Hep C RNA

22
Q

Hepatitis C from?

A

Intravenous drug user (IVDU), blood, sex

23
Q

Hepatitis C causes?

A

Mild can get cirrhosis

24
Q

Hepatitis C treatment?

A

Manage as chronic

25
Q

Hepatitis A investigation?

A

ELISA - IgM antibody positive

26
Q

Hepatitis A causes?

A

Fever/malaise/arthralgia/jaundice/rigor

27
Q

Hepatitis A treatment?

A

Supportive

28
Q

Influenza A/B investigation? x2 (not that important)

A

RNA

NAAT/complement fixation

29
Q

Influenza A/B causes?

A

Fever/malaise/arthralgia

30
Q

Influenza A/B treatment?

A

Supportive

Flu vaccine

31
Q

Respiratory Syncytial Virus causes?

A

Bronchiolitis (infants)

Croup

32
Q

Morbillivirus investigation x2?

A

Inclusion bodies

IgM +ve

33
Q

Morbillivirus causes?

A

Measles

34
Q

Enterovirus causes?

A

Measles

35
Q

Enterovirus investigation?

A

Culture the CSF

36
Q

Rubivirus causes?

A

German measles/Rubella

37
Q

Rubivirus investigation?

A

Rubella-specific IgM +ve

38
Q

Rubivirus treatment?

A

MMR vaccine (prevent), no treatment

39
Q

Paramyxovirus test?

A

Salivary IgM +ve

40
Q

Paramyxovirus causes?

A

Mumps

41
Q

Paramyxovirus treatment?

A

Supportive

42
Q

Parvovirus investigation?

A

ELISA - IgM +ve (acute and will produce IgG so long-term protected)

43
Q

Parvovirus causes?

A

Slapped cheeks

44
Q

Parvovirus treatment?

A

Supportive