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HDM Final F19 > Viruses > Flashcards

Viruses Flashcards

1
Q

Poxviridae

A 
Type: DNA
Shape: Complex
Characteristic: Enveloped
Genetic material: DS-cov lined
Polymerase (+)
B class: I
Viruses & Disease: Variola (Smallpox), Monkey Pox (mild Smallpox), Mollaskum Contagiosum (long-lasting raised skin lesions; may have to be surgically removed)
Systematic
Persistent: Acute
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2
Q

Herpesviridae

A 
Type: DNA
Shape: Icosahedral
Characteristic: Enveloped
Genetic material: DS linear
Polymerase (-)
B class: I
Viruses & Disease: Alpha [HSV 1 (Cold sores), HSV (Genital herpes), VZV (Chicken pox/Shingles)]; Beta [HCMV (human cytomegalovirus) (congenital CMV disease/ CMV Retinitis), HHV6 (Roseola), HHV7 (Orphan Virus)]; Gamma [EBV (Hairy Leukoplakia/ Nasopharyngeal carcinoma/Burkitt's Lymphoma), HHV8/KSHV (Karposi's sarcoma)]
Method of Entry: Fusion
Systematic
Persistent: Alpha &Beta (Acute/Latent), Gamma (Acute/Chronic/Latent, *except Karposi's Sarcoma)
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3
Q

Hepadnaviridae

A 
Type: DNA
Shape: Icosahedral
Characteristic: Enveloped
Genetic material: DS circular
Polymerase (+)
B class: I
Viruses & Disease: Hep B (Hepatitis)
Systematic
Persistent: Acute/Chronic 10%
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4
Q

Adenoviridae

A 
Type: DNA
Shape: Icosahedral
Characteristic: Naked
Genetic material: DS linear
Polymerase (-)
B class: I
Viruses & Disease: Serotype dependent (Respiratory, GI, Conjunctiva (lymphoid tissue))
Method of Entry: Endocytosis
Systematic
Persistent: Acute/Chronic/Latent
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5
Q

Papillomaviridae

A 
Type: DNA
Shape: Icosahedral
Characteristic: Naked
Genetic material: DS circular
Polymerase (-)
B class: I
Viruses & Disease: HPV 16, 18, 31, 33, 34, 45, 52 (Penile/Cervical/Anal/Oropharyngeal cancer), HPV non cancer causing (Warts)
Local
Persistent: Acute
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6
Q

Polyomaviridae

A 
Type: DNA
Shape: Icosahedral
Characteristic: Naked
Genetic material: DS circular
Polymerase (-)
B class: I
Viruses & Disease: BK virus (Kidney disease), JC virus (Progressive brain disease)
Systemic
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7
Q

Parvoviridae

A 
Type: DNA
Shape: Icosahedral
Characteristic: Naked
Genetic material: SS linear
Polymerase (-)
B class: II
Viruses & Disease: Parvo virus B19 (Erythrovirus (Fifths Disease))
Systemic
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8
Q

Orthomyxoviridae

A 
Type: RNA
Shape: Helical
Characteristic: Enveloped
Genetic material: (-) SS 8 seg
Polymerase (+)
B class: V
Viruses & Disease: Influenza A, B & C (Respiratory Tract Infection)
Local/Systematic
Persistent: Acute
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9
Q

Bunyaviridae

A 
Type: RNA
Shape: Helical
Characteristic: Enveloped
Genetic material: (-) SS 3 seg
Polymerase (+)
B class: V
Viruses & Disease: Hanta Virus Pulmonary Syndrome (Hemorrhagic fever w/ renal syndrome)
Local/Systematic
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10
Q

Arenaviridae

A 
Type: RNA
Shape: Helical
Characteristic: Enveloped
Genetic material: (-) SS 2 seg
Polymerase (+)
B class: V
Viruses & Disease: Lymphocytic Choriomeningitis (Febrile flu like myalgia/Meningitis), Lassa virus (Lassa fever, severe symptomatic illness, increased vascular permeability, shock), June virus (Argentinian hemorrhagic fever, more bleeding than Lassa virus), Machupo virus (Bolivian hemorrhagic fever) 
Local/Systematic
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11
Q

Paramyxoviridae

A 
Type: RNA
Shape: Helical
Characteristic: Enveloped
Genetic material: (-) SS
Polymerase (+)
B class: V
Sub Family: Morbillivirus
Viruses & Disease: Measles virus (Measles/Subacute Sclerosing Panencepholitis) [systemic, acute/chronic], Mumps virus (Mumps) [systemic, acute], Paramyxo virus (Parainfluenza viruses type 1-4) [local, acute], Respiratory syncytial virus (RSV) (Respiratory disease, can be fatal in babies) [local, acute]
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12
Q

Rhabdoviridae

A 
Type: RNA
Shape: Helical
Characteristic: Enveloped
Genetic material: (-) SS
Polymerase (+)
B class: V
Viruses & Disease: Rabies virus (hydrophobia, seizures, hallucinations, paralysis, coma, death)
Method of Entry: Endocytosis 
Systematic
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13
Q

Filoviridae

A 
Type: RNA
Shape: Helical
Characteristic: Enveloped
Genetic material: (-) SS
Polymerase (+)
B class: V
Viruses & Disease: Ebola virus (Ebola hemorrhagic fever)
Systematic
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14
Q

Coronaviridae

A 
Type: RNA
Shape: Helical
Characteristic: Enveloped
Genetic material: (+) SS
Polymerase (-)
B class: IV
Viruses & Disease: Corona virus (Cold virus) (respiratory infection, common cold (can be severe: SARS, MERS))
Local
Persistent: Acute
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15
Q

Retroviridae

A 
Type: RNA
Shape: Icosahedral
Characteristic: Enveloped
Genetic material: (+) SS 2 copies
Polymerase (+)
B class: VI
Viruses & Disease: HTLV 1 (Adult T cell leukemia) [Acute], HIV 1 & 2 (AIDS) [Acute/Chronic/Latent]
Method of Entry: Fusion
Systematic
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16
Q

Togaviridae

A 
Type: RNA
Shape: Icosahedral
Characteristic: Enveloped
Genetic material: (+) SS
Polymerase (-)
B class: IV
Viruses & Disease: Rubella virus (Rubella), Alpha viruses (Mosquito borne illnesses), Chikungunya virus (arthralgia, arthritis, encephalitis in very young and old)
Systematic
Persistent: Chronic (Rubella only)
17
Q

Flaviviridae

A 
Type: RNA
Shape: Icosahedral
Characteristic: Enveloped
Genetic material: (+) SS
Polymerase (-)
B class: IV
Viruses & Disease: Hep C (Hepatitis/carcinoma/cirrhosis), Yellow Fever virus (Hemorrhagic Fever), Dengue virus (Dengue fever, broken bone fever, hemorrhagic fever/shock), West Nile Virus (Fever, encephalitis), Zika virus (Fever, birth defects if mother infected early in pregnancy)
Systematic
Persistent: Acute/Chronic 70% (Hep C only), rest Acute
18
Q

Picornaviridae

A 
Type: RNA
Shape: Icosahedral
Characteristic: Naked
Genetic material: (+) SS
Polymerase (-)
B class: IV
Viruses & Disease: Rhino Virus (Upper respiratory infection) [local, acute]
Entero virus (Poliovirus-paralytic disease, meningitis, encephalitis, [systemic], Echovirus B- myocarditis, encephalitis, meningitis, [systemic], Coxsackievirus B- hand, foot, mouth disease (herpangia),[local/systematic, acute], Coxsackievirus A- myocarditis, encephalitis, meningitis), [localsystematic, acute], Hep A virus (hepatitis), [systematic]
19
Q

Caliciviridae

A 
Type: RNA
Shape: Icosahedral
Characteristic: Naked
Genetic material: (+) SS
Polymerase (-)
B class: IV
Viruses & Disease: Norovirus (Gastroenteritis)
Method of Entry: blood group Ag's in saliva
Local/Systematic
20
Q

Hepeviridae

A 
Type: RNA
Shape: Icosahedral
Characteristic: Naked
Genetic material: (+) SS
Polymerase (-)
B class: IV
Viruses & Disease: Hep E (Hepatitis)
Systematic
21
Q

Reoviridae

A 
Type: RNA
Shape: Icosahedral
Characteristic: Naked
Genetic material: DS 10-12 seg
Polymerase (+)
B class: III
Viruses & Disease: Rotavirus (Gastroenteritis)
Local/Systematic
Persistent: Acute

HDM Final F19 (3 decks)

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