Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Micro > Viruses > Flashcards

Viruses Flashcards

1
Q

Influenza (types A B and C)

A

+HA +NA
- ss RNA
Flu = fever, rhinitis, cough, myalgias, arthralgias etc
Reyes sx = children + aspirin + flu = liver/brain disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

parainfluenza

A 
\+HA +NA +F 
- ss RNA
adults = bronchitis, pharyngitis, rhinitis
kids/elderly = viral pneumonia 
croup = barking cough
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

respiratory syncytial virus (RSV)

A

-HA -NA +F
- ss RNA
MCC pneumonia < 6 mos
acute otitis media

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

metapneumovirus

A

integrin alpha-V-beta receptor
- ss RNA
upper/lower resp infxns in kids/elderly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

mumps

A 
\+HA +NA +F 
- ss RNA
Mumps:
parotid gland swelling
testicular swelling
meningitis 
encephalitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

measles (rubeola)

A

+HA -NA +F
- ss RNA
Measles:
prodrome = high fever, hacking cough, conjunctivitis
kopliks spots = red based blue-white centered lesions in mouth
rash = spreads from head to toe (like paint)
subacute aclerosing panencephalitis = slow encephalitis many yrs after measles infxn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

hepatitis A

A

+ ss RNA
Acute viral hepatitis = fever, jaundice, painful hepatomegaly
NEVER BECOMES CHRONIC
anti-HAV IgM = active disease
anti-HAV IgG = old; no active disease (protective)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

hepatitis B

A

ds circular DNA
Dane particle = envelope + capsid assoc proteins + capsid + core (DNA + enzymes)
dissociation of dane particle leaves HBsAg and HBcAg
carries DNA polymerase in virion

acute viral hepatitis = fever, jaundice, painful hepatomegaly
fulminant hepatitis = severe acute hepatitis w/ rapid destruction of liver
chronic hepatitis:
asx carrier
chronic peristent hepatitis
chronic active hepatitis

HBsAg = disease
anti-HBsAg = immunity 
IgM anti HBcAg = new infection 
IgG anti-HBcAg = old infection 
HBeAg = high infectivity 
anti-HBeAg = low infectivity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

hepatitis C

A 
ss RNA
acute viral hepatitis 
85% develop chronic 
20% develop cirrhosis 
risk of hepatocellular carcinoma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

hepatitis D

A

incomplete RNA virus –> needs HBV (HBsAg)

anti-HBV abs help cure infxn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

hepatitis E

A

ss RNA

similar to hepatitis A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

hepatitis G

A

no evidence of liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

herpes simplex virus 1 (HSV-1)
herpes simplex virus 2 (HSV-2)
varicella-zoster virus

A 
ds linear DNA
gingivostomatitis (cold sores)
herpetic keratitis of the eye
encephalitis (MCC of viral encephalitis in US)
genitial herpes 
neonatal herpes (TORCHES)
herpetic whitlow
varicella (chicken pox) 
zoster (shingles)
herpes zoster ophthalmicus --> can lead to blindness
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

cytomegalovirus

A 
ds linear DNA
asx 
congenital disease (TORCHES)
CMV mononucleosis 
immunocompromised --> pneumonia retinitis esophagitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

epstein barr virus

A

ds linear DNA
infectious mononucleosis = fever sore throat severe lethargy enlarged nodes and spleen
burkitts B cell lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

human herpesvirus 6

A

ds linear DNA

roseola (exanthum subitum) = high fever followed by rash on trunk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

human herpesvirus 8

A

ds linear DNA

kaposis sarcoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

poxviridae

A

complex coat
smallpox = skin lesions –> DEATH
molluscum contagiosum = small white bumps w/ central dimple in genital region

19
Q

papovaviridae

A

ds circular DNA
HPV= warts
BK polyomavirus = kidney dis in kidney transplant, hemorrhagic cystitis in BMT
JC polyomavirus = leukoencephalopathy –> degenerative CNS white matter disease

20
Q

adenoviridae

A

ds circular DNA
upper resp tract infxn = fever sore throat fever conjunctivitis
epidemic keratoconjunctivitis (pink eye)
epidemic diarrheal illness in infants/kids

21
Q

parvoviridae

A
  • ss linear DNA
    erythema infectiosum (fifth disease) affects kids 4-12:
    fever and slap cheek rash
    transient aplastic anemia crisis = parvovirus stops production of RBCs in BM
22
Q

togaviridae alpha virus
WEE
EEE
VEE

A

+ ss RNA
vector = mosquito
HA, fever, altered level of consciousness, focal neurologic deficits

23
Q

togoviridae alpha virus

chikungunya

A

fever rash joint pain

chronic arthritis

24
Q

togaviridae rubivirus

A 
rubella:
fever 
lymphadenopathy
flulike sxs 
rash from forehead to face to torso to extremities (3 days)

congenital defects (TORCHES)

25
Q

flaviviridae yellow fever virus

A

+ ss RNA
hepatitis –> jaundice
fever
backache

26
Q

flaviviridae dengue fever

A 
"break bone fever"
\+ ss RNA 
HA
mm aches
joint aches 
backache

dengue hemorrhagic fever = hemorrhage thrombocytopenia and septic shock (more likely with recurrent infxns)

27
Q

flaviviridae St. Louis, Japanese, West Nile encephalitis

A

encephalitis

fever

28
Q

flaviviridae west nile virus

A

fever
meningitis
encephalitis or myelitis that produces flaccid paralysis

29
Q

bunyaviridae
california encephalitis
rift valley fever
sandfly fever virus

A
  • ss RNA
    arthropod vector

fever
encephalitis
rift valley fever can also cause hemorrhagic manifestations

30
Q

bunyaviridae hantavirus

A
  • ss RNA
    hemorrhagic fever w/ renal syndrome
    hantavirus pulmonary sx = fever, mm aches, cough, nausea/vomit, pulmonary edema –> resp failure, 40% mortality
31
Q

enteroviridae poliovirus

A

+ ss RNA
mild febrile illness (infants)
aseptic meningitis
paralytic poliomyelitis = flaccid paralysis d/t necrosis of large motor neurons

32
Q

enteroviridae coxsackie A

A

+ ss RNA
cold
rashes
viral meningitis
herpangina = fever, sore throat, small vesicles in back of throat
hand foot and mouth disease (kids < 5) = vesicles on hands, foot and mouth, highly contagious

33
Q

enteroviridae cocksackie B

A

+ ss RNA
viral meningitis
myocarditis/pericarditis
pleurodynia

34
Q

enteroviridae echoviruses

A

+ ss RNA
cold
rashes
viral meningitis pericarditis

35
Q

rhinoviridae rhinovirus

A

+ ss RNA

common cold

36
Q

astrovirus

A

+ ss RNA

diarrheal illness

37
Q

norwalk virus

A

+ ss RNA

viral gastroenteritis = fever, abdominal pain, vomiting, diarrhea (no pus no blood)

38
Q

rotavirus

A

ss RNA
viral gastroenteritis = fever abdominal pain vomiting diarrhea (no blood no pus)
severe dehydration

39
Q

coronavirus

A

+ ss RNA

common cold

40
Q

rhabdoviridae

A
  • ss RNA
    Rabies:
    prodrome = fever HA sore throat and very sensitive nn around wound site
    acute encephalitis = confusion and seizures
    classic brain stem encephalitis = crainal nn dysfxn, contraction of pharyngeal mm –> foaming of the mouth
    DEATH
41
Q

marburg virus

ebola virus

A
  • ss RNA
    acute viral hemorrhagic fever –> high mortality (50-90%)
    2 wks incubation
    abrupt onset of fever, HA, myalgia, abdom pain, diarrhea, pharyngitis, hiccups, cough, and somnolence
42
Q

lymphocytic choriomeningitis virus (LCM)

A
  • ss RNA

influenza like illness sometimes assoc w/ viral meningitis
occasionally fatal

43
Q

Lassa fever

A
  • ss RNA

fever, sore throat, abdom pain, inractable vomiting and hypotension
fatal in half of cases

44
Q

south american hemorrhagic fever viruses

A
  • ss RNA

gradual onset of fever myalgias nausea abdom pain conjuctivitis sometimes gen lymphadenopathy. later bleeding and petechiae. sometimes tremor seizures diarrhea.

Micro (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions