Spriochetes Flashcards
Treponema pallidum
Syphilis:
primary = painless chancre
secondary = rash on palms/soles, condyloma latum
latent = 25% relapse to secondary
tertiary = gummas of skin/bone, CV, neurosyphilis (Argyll-robertson pupil)
congenital syphilis
treponema pallidum subspecies endemicum
BEJEL = primary and secondary lesions of oral mucosa. tertiary lesions = gummas of skin/bone
treponema pertenue
YAWS = primary and secondary lesions near site of infxn, tertiary lesions = gummas of skin/bone
causes severe disfigurement of the face –> gangosa
treponema carateum
PINTA = flat red or blue lesions that do NOT ulcerate
borrelia burgdorferi
lyme disease”
stage 1: erythema chronicum migrans (ECM)
stage 2: aseptic meningitis, CN palsies, peripheral neuropathy, myocarditis, arthritis
stage 3: encephalopathy
borrelia recurrentis
relapsing fever every 8 days
rash splenomegaly
leptospira interrogans
1st phase (leptospiremic) = high fever, HA, severe mm aches, photophobia 2nd phase (immune) = emergence of IgM, meningismus Weils disease = severe leptospirosis, renal failure, hepatitis, mental changes, hemorrhages
Mycobacterium tuberculosis
primary tuberculosis = asx
secondary = lowgrade fever, night sweats, weight loss, productive cough (may be blood), lymph node TB (scrofula), Pott’s disease, chronic arthritis, miliary TB
mycobacterium leprae
lepromatous (low cell mediated immunity) = multiple skin lumps, leonine facies, saddle nose, peripheral neuropathy , blindness
tuberculoid = 1 or 2 superficial lesions
mycobacterium avium complex
in AIDS pts fever (FUO) weight loss hepatitis diarrhea high alkaline phosphatase in CBC
mycoplasma pneumoniae
trachebronchitis walking pneumonia (atypical pneumonia) = fever w/ dry cough
ureaplasma urealyticum
urethritis
burning on urination
yellow discharge from urethra
