Viruses Flashcards
1 cause of non bacterial diarrhea in erudite
Norwalk virus
1 cause of viral diarrhea in children
Rotavirus
Rotavirus
Family , type of genome , replication
Reovirus
Segmented dsRNA - 11 segments
Naked wheel like icosahedral capsid
Replications in cytoplasmic inclusions .. Released by cell lysis
Transmission of rotavirus
Fecal oral,resists drying. Fomites
Fall, winter early spring
Norwalk virus
Naked , small , round ss +RNA with 3 reading frames
Very very hardy
More adults than children
Fecal oral, shellfish - yr round - hotels, cruise ship outbreaks
Pathophys Norwalk
Binds to brush boarder
Blunted villi at jejunum w. Cytoplasmic vacuolatioj mononuclear cell infiltrate
Vomiting diarrhea no blood
Enteric adenovirus
Naked dsDNA stereotypes 40.41 - gastroenteritis
Similar. Pathogenesis as rota
Astrovirus
SsRNA
Children and nursing home residents