viruses Flashcards
the structure of a virus
-tiny non cellular structures
-have an outer protein coat called a capsid
-in some viruses the capsid is enclosed in a complex out membrane
-inside is a nucleic acid either DNA or RNA
-viral genes carry instructions to form new viruses
-have no ribosomes, mitochondria or other cytoplasmic organelles
-they don’t carry out metabolic reactions, they need a host to do it for them instead
living features of viruses
-contain genetic material (DNA or RNA)
-have a protein coat
-can replicate inside a living host cell
non living features of viruses
-non cellular and don’t carry out metabolic reactions
-cannot reproduce independently
-have no ribosomes, mitochondria or any other cell organelles
-only have one type of nucleic acid, either DNA or RNA
shapes of viruses
-round shaped
-rod shaped
-complex in shape
virus replication
-they are not cells so they cannot reproduce
-we say replicate instead of reproduce
-they can only multiply by using the energy and structures of a living host cell
-they are obligate parasites
what is bacteriophage
-a virus that infects bacteria
-the most complex and studied of all viruses
-replication takes about thirty minutes
-the way most viruses infect human cells
the first stage of replication in bacteriophage
attachment
-virus attaches to host cell
-proteins from virus match receptors sites on a host cell
this is why only certain viruses can infect certain host cells
second stage of replication in bacteriophage
entry
-virus forms a hole in the host cell and viral nucleic acid is pushed through
-the protein coat of a bacteriophage stays outside while protein of other viruses enter animal cells and are broken down
third stage of replication in bacteriophage
synthesis
-the host nucleic acid is made inactive
-the viral nucleic acid uses the host organelles to produce new viral nucleic acids and proteins (capsid)
fourth stage of replication in bacteriophage
assembly
-new viruses are made inside host cell using viral molecules that have been produced
final stage of replication in bacteriophage
release
-the host cell bursts to release between 100 and 100,000 new viruses
what is the bursting of a host cell called
lysis
retroviruses
-contain RNA and an enzyme that converts the virus RNA to DNA
-this DNA makes new copies of the virus RNA and new viruses inside the host cell
-some viruses do not destroy the host DNA
give an example of a retro virus
HIV
what happens when a virus that does not destroy the host DNA
-the viral DNA intergrates with the host DNA and remains inactive
-when the host DNA is copied the viral DNA is copied and passed onto daughter cells
disadvantages of viruses
- human disease: cold, flu, polio, rabies, mumps, measles, chickenpox, warts etc
- plant diseases: tobacco mosaic disease, potato and tomato mosaic disease
- animal diseases: rabies-transferred by saliva and can cause choking, paralysis or death
foot and mouth- causes blisters in feet and mouth
benefits of viruses
-can be used to transfer genes from one organism to another in genetic engineering, these viruses are called vectors
-control of infection, bacteriophage can be used to control bacterial infections, they help to reduce infection due to antibiotic resistant bacteria
what is AIDS
acquired immune deficiency syndrome
-a person cannot make antibodies due to infection with human immunodeficiency virus (HIV)
-HIV enters body in fluids such as blood or semen
effects of AIDS
-enters a white blood cell and either remains dormant or disables the cell
-when the virus lays dormant other white blood cells produce antibodies against it.
-if present in a blood sample a person is HIV positive, these antibodies do not disable the virus as it mutates too quickly
-it affects the lymphocytes called helper T-cells which prevents a person from producing antibodies
-an AIDS sufferer usually dies from a common infection they would normally fight off eg pneumonia
control and immunity of viruses
-antibodies produced by white blood cells will kill viruses
-we become immune to viruses after we have had a viral infection (natural immunity)
-if we are vaccinated against them (artificial immunity) eg flu vaccine
-antibiotics do not kill viruses