Virus Life Cycle Flashcards
Do viruses replicate outside the cell?
No they only replicate within the cell.
Do viruses have genes for biosynthetic molecules?
No.
Cells with receptors that can bind to virus proteins are called what?
Susceptible.
Being permissive means what?
Cells that support virus replication and virion synthesis
What is an abortive infection?
Replication is incomplete.
What is tissue tropism?
The cell type preferred by the virus
What are the two main types of viral entry?
Fusion and Endocytosis
Uncoating marks the start of what phase?
Eclipse phase
What must all viruses make?
mRNA, to make protein, to make more virulence
What makes a cell permissive?
The host cell has to accept the mRNA produced by the virus, there needs to be a match
Do viruses translate their mRNA?
No, without exception this task is performed by the host, the host uses its own Ribosomes, tRNAs, and Amino Acids
What are the key points of caspid assembly?
They are usually made late in the infection,
two forms are icosahedral and helical,
they can mature outside the host cell via enzymatic interactions
What are the major mechanisms of virions escaping the cell?
Budding, Exocytosis, Lysis, Cell to Cell Spread
What is a name for cell fusion?
Syncytium formation, this is induced by a virus and will result in cell death.
How are infectious virions measured in culture?
Plaque forming Units (PFU)
