Virulence Gene Flashcards
1
Q
What is a virulence gene??
A
- A gene that encodes a virulence factor
- loss of such a gene, by mutation or by loss of a plamid, DECREASES virulence
2
Q
ViG 1
A
5-10% of genes in Vibrio cholerae and Salmonella typhimurium encode virulence factors
3
Q
ViG 2-Location A
A
often located on mobile genetic elements (eg plasmids)
4
Q
ViG 3-Location B
A
…can also be located in LARGE, LOCALIZED regions of the chromosome–“PATHOGENICITY ISLANDS”
5
Q
ViG 4-PATTiS
A
Pathogenicity islands often absent in closely related NON-PATHOGENIC strains
