Gene Networks & Signal Transduction

Question 1

What must cells do to adapt to large environmental changes?

Answer 1

They must regulate LARGE batteries of OPERONS

Question 2

We are groups of genes that are INDEPENDENTLY controlled as members of DIFFERENT operons, what must we do?

Answer 2

We must COOPERATE to accomplish some response to an environmental change

Question 3

What happens to different subsets?

Answer 3

Some are turned ON while otheres are turned OFF. This is done simultaneously-yayyy, multi-tasking.

Question 4

What do global regulatory systems do?

Answer 4

Regulated MANY virulence factors.

Question 5

What is a REGULON?

Answer 5

A group of operons (also called global control system) subject to the control of a common (or global) REGULATOR

Question 6

Step 1

Answer 6

Through the action of some sensor molecule, a cel sense a stimulus

Question 7

Step 2

Answer 7

Sensor signals to activate/DEactivate a regulator

Question 8

Step 3

Answer 8

regulator binds to several operons

Question 9

Step 4

Answer 9

binding turns some ON and some OFF

Question 10

Step 6

Answer 10

gene products respond to the original stimulus

Question 11

Step 6

Answer 11

gene products exert FEEDBACK CONTROL on their own expression

Question 12

Is gene regulation a commoner?

Answer 12

NO! It’s HEIRARCHICAL, bitchesss

Question 13

The ToxR Regulon

Answer 13

one stimulus, many products-one of which: Cholera toxin (Ctx-Beta)