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STEP 1: MIcro > Virology Memorization > Flashcards

Virology Memorization Flashcards

1
Q

What vaccines are live attenuated viruses?

A
  1. Smallpox
  2. Yellow Fever
  3. Sabin Polio (OPV)
  4. MMR
  5. Nasal Flu
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2
Q

What vaccines are killed viruses?

A
  1. Rabies
  2. Injected Flu
  3. HAV
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3
Q

What type of vaccine is HBV?

A

Recombinant - HBsAg

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4
Q

What type of vaccine is HPV?

A

Recombinant - HPV 6, 11, 16, 18

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5
Q

What viruses have DNA genomes? Which one is ss?

A 
Herpesviruses - HSV, EBV, CMV, VZV
Hepadnevirus - HBV
Adenovirus
Parvovirus (ss) - B19
Papillomavirus - HPV
Polyomavirus - JC, BK
Poxvirus - Smallpox, vaccinia (cowpox), m. contagiosum

HHAPPPPy viruses

All are ds except Parvo (ss)

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6
Q

What DNA viruses have a circular genome?

A

Papillomavirus (HPV)
Polyomavirus (JC and BK)
Hepadnavirus (HBV)

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7
Q

What is the only dsRNA virus?

A

Reovirus (repeatovirus)

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8
Q

Are viruses haploid or diploid?

A

All are haploid except HIV (which is diploid - two identical copies of ssRNA genome)

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9
Q

What is the only DNA virus to replicate in the cytoplasm?

A

Poxviruses (smallpox, vaccinia, m. contagiosum)

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10
Q

What is the only RNA virus to replicate in the nucleus?

A

Influenza

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11
Q

Where do enveloped viruses get their envelope?

A

From plasma membrane, except herpesviruses (gets it from the nuclear membrane)

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12
Q

What are the naked viruses?

A 
Papilloma
Adeno
Picorna
Polyoma
Calci
Parvo
Reo
Hepevirus

“PAPP smears and CPR for NAKED Heppy (hippy)”

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13
Q

DNA viruses?

A 
Hepadna
Herpes
Adeno
Pox
Parvo
Papilloma
Polyoma

“HHAPPPPy viruses”

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14
Q

What are the polyomaviruses?

A

JC - PML in HIV pts

BK - kidney dz in transplant pts

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15
Q

What are the pox viruses?

A

Smallpox
Vaccinia (cowpox)
Molluscum contagiosum

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16
Q

What is the Hepadnavirus?

A

HBV

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17
Q

What is the parvovirus? What does it cause?

A

B19 - “slapped cheek” 5th disease; aplastic crisis in Sickle cell dz

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18
Q

What is the largest DNA virus?

A

Pox - replicates in cytoplasm

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19
Q

What virus can cause temporal lobe encephalitis?

A

HSV-1

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20
Q

Mononucleosis?

A

EBV (+ monospot) and CMV (- monospot)

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21
Q

What virus causes roseola?

A

HHV-6, high fever for days then diffuse rash

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22
Q

What virus causes Kaposi?

23
Q

Owl’s eye inclusions?

24
Q

Test of choice for HSV dx?

25
Q

Tzanck smear?

A

HSV-1, -2, VZV

26
Q

What cells do EBV infect? Via what?

A

B cells via CD21

27
Q

Atypical lymphocytes in mono are what?

A

REACTIVE CYTOTOXIC T CELLS (not infected B cells)

28
Q

What kind of virus is norovirus?

A

Reo, so it is dsRNA

29
Q

What are the picornaviruses?

A

PERCH

Polio
Echo
Rhino
Coxsackie
HAV
30
Q

What are the - sense RNA viruses?

A 
Arena
Bunya
Paramyxo
Orthomyxo
Filo
Rhabdo
31
Q

What are the + sense RNA viruses?

A 
Picorno
Hepevirus
Calici
Flavi
Toga
Retro
Corona
32
Q

What are the hepeviruses?

33
Q

What are the flaviviruses?

A 
HCV
Yellow fever
Dengue
St. Louis
West Nile
34
Q

What are the togaviruses?

A

Rubella

Eastern/Western equine encephalitis

35
Q

What are the retroviruses?

36
Q

What are the coronaviruses?

A

coronoavirus - SARS/common cold

37
Q

What are the orthomyxoviruses?

38
Q

What are the paramyxoviruses?

A

Parainfluenza - croup
RSV
Measles
Mumps

39
Q

What are the rhabdoviruses?

40
Q

What are the filoviruses?

41
Q

What are the Arenaviruses?

A

LCMV

Lassa fever

42
Q

What are the bunyaviruses?

A

California encephalitis
Sandlfy/Rift valley fever
Crimean-Congo hemorrhagic fever
HANTAVIRUS –> ARDS

43
Q

What are the deltaviruses?

44
Q

How are picornaviruses spread?

A

All by fecal-oral except rhinovirus (which is acid labil)

45
Q

Common cold?

A

Rhino virus

46
Q

Infantile gastroenteritis?

47
Q

Rash that starts on head and moves down?

A

Rubella (part of ToRCHeS)

48
Q

All paramyxoviruses have what? What is the tx?

A

F protein (Fusion)

Palivizumab = mab for F protein

49
Q

What is the target of tamiflu?

A

Neuramidase

50
Q

Koplik spots?

A

Red spots whit white center on buccal mucosa

Measles

51
Q

What is a long term sequelae of measles?

A

SSPE - subacute sclerosing panencephalitis

52
Q

What are the symptoms of Mumps?

A

Parotitis
Orchitis
Meningitis

Parotid and testes as bigs as POM-poms

53
Q

How does HCV change its antigens?

A

Lacks 3’–>5’ endonuclease so it is prone to mistakes.

54
Q

What is the clinical definition of AIDS?

A

CD4+ less than 200 or an AIDS defining infection

STEP 1: MIcro (5 decks)

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