Virology Blitz Flashcards
Enveloped DNA viruses
Herpes, Hep B and Smallpox
Nonenveloped DNA virus
Parvo-, adeno-, papilloma-virus
Nonenveloped RNA viruses
Entero, rhino and reo
Enveloped RNA virus
Influenza and parainfluenza, RSV, MMR, rabies, HTLV, HIV
Acute febrile illness associated with abrupt onset of HA, myalgias, fever leading to rash, shock, and bleeding
Ebola
Mammalian filamentous virus
Ebola virus
Filoviruses such as Marburg virus and Ebola virus can cause what disease?
Hemorrhagic fevers
Biosafety level of Ebola and Marburg virus
Level 4
Ebola virus specie in the Philippines
Reston
Monkey for Reston (Ebola virus)
Cynomolgus Macaques
Incubation period of 7-10 days
Flu-like sxs continued fever joined by diarrhea, chest pain (associated with cough), prostration, depressed mentation with maculopapular rash (day5-7) followed by desquamation
Ebola virus
Herpangina, HFMD are caused by what virus
Coxsackie Also
Pleurodynia (Bornholm disease), myocarditis, pericarditis are caused by what virus?
Coxsackie B
Group of rotavirus that is the principal cause of human disease
Group A rotavirus
Groups of rotavirus that are known to cause disease in humans
Groups A, B, C
Virus that is the leading cause of morbidity among Filipino children and 5th leading cause of infant mortality
Rotavirus
Gold standard for diagnosing rotavirus
Viral culture
4 conditions that are associated with Parvoviridae
Erythema infectiosum
Pure red cel aplasia
Transient aplastic crisis
Hydrops fetalis
Slapped cheek appearance + lacy appearing rash
Erythema infectiosum, fifth’s disease, parvovirus B19
HHV6, 6th disease, exanthem subitum, 6months to 2 years
Roseola
Only DNA virus that replicates in the cytoplasm
Poxvirus
Poxvirus infection that is more virulent
Variola
Poxvirus infection that is less virulent
Vaccinia
Who introduced vaccination with live cowpox virus in 1798?
Edward Jenner
Control of smallpox by deliberate infection with mild forms (i.e. Vaccinia) of the disease
Variolation
Inclusion bodies in Small pox
Guarnieri bodies
Inclusion bodies of Rubeola
Warthin finkeldey bodies
Inclusion bodies of Molluscum contangiosum
Henderson-Peterson bodies
Dermatome affected in Shingles
Thoracic
Tzanck smear is an assay used for:
HSV and VSV
DOC for CMV
Ganicyclovir
Heterophile positive
Heterophile negative
Heterophile positive EBV
Heterophile negative CMV
Monospot test or Heterophile antibody test (Paul-Bunnel) is diagnostic of what disease?
Infectious mononucleosis
What to look for Monospot test?
Agglutination of RBCs
HHV8 is associated with what conditions?
Kaposi sarcoma, AIDS associated B-cell lymphoma, multiple myeloma
Primary method for detection of HHV8
PCR amplication
Enzyme used for PCR amplication
Taq polymerase (heat stable enzyme)
HPV16 and HPV18 associated in CIN mechanism
Inactivation of tumor suppressor proteins p53 and p110-Rb by viral protein E6 and E7
HPV 1, 2, 4 causes?
Plantar warts
Exanthematous phase of measles
Red maculopapular eruption beginning on forehead (around the hairline), behind the ears, and on upper neck spreading downwards to the torso and extremities
Most common complication of measles
Otitis media
