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Hi-Yield for PLE > Virology Blitz > Flashcards

Virology Blitz Flashcards

1
Q

Enveloped DNA viruses

A

Herpes, Hep B and Smallpox

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2
Q

Nonenveloped DNA virus

A

Parvo-, adeno-, papilloma-virus

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3
Q

Nonenveloped RNA viruses

A

Entero, rhino and reo

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4
Q

Enveloped RNA virus

A

Influenza and parainfluenza, RSV, MMR, rabies, HTLV, HIV

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5
Q

Acute febrile illness associated with abrupt onset of HA, myalgias, fever leading to rash, shock, and bleeding

A

Ebola

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6
Q

Mammalian filamentous virus

A

Ebola virus

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7
Q

Filoviruses such as Marburg virus and Ebola virus can cause what disease?

A

Hemorrhagic fevers

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8
Q

Biosafety level of Ebola and Marburg virus

A

Level 4

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9
Q

Ebola virus specie in the Philippines

A

Reston

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10
Q

Monkey for Reston (Ebola virus)

A

Cynomolgus Macaques

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11
Q

Incubation period of 7-10 days
Flu-like sxs continued fever joined by diarrhea, chest pain (associated with cough), prostration, depressed mentation with maculopapular rash (day5-7) followed by desquamation

A

Ebola virus

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12
Q

Herpangina, HFMD are caused by what virus

A

Coxsackie Also

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13
Q

Pleurodynia (Bornholm disease), myocarditis, pericarditis are caused by what virus?

A

Coxsackie B

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14
Q

Group of rotavirus that is the principal cause of human disease

A

Group A rotavirus

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15
Q

Groups of rotavirus that are known to cause disease in humans

A

Groups A, B, C

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16
Q

Virus that is the leading cause of morbidity among Filipino children and 5th leading cause of infant mortality

A

Rotavirus

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17
Q

Gold standard for diagnosing rotavirus

A

Viral culture

18
Q

4 conditions that are associated with Parvoviridae

A

Erythema infectiosum
Pure red cel aplasia
Transient aplastic crisis
Hydrops fetalis

19
Q

Slapped cheek appearance + lacy appearing rash

A

Erythema infectiosum, fifth’s disease, parvovirus B19

20
Q

HHV6, 6th disease, exanthem subitum, 6months to 2 years

A

Roseola

21
Q

Only DNA virus that replicates in the cytoplasm

A

Poxvirus

22
Q

Poxvirus infection that is more virulent

A

Variola

23
Q

Poxvirus infection that is less virulent

A

Vaccinia

24
Q

Who introduced vaccination with live cowpox virus in 1798?

A

Edward Jenner

25
Q

Control of smallpox by deliberate infection with mild forms (i.e. Vaccinia) of the disease

A

Variolation

26
Q

Inclusion bodies in Small pox

A

Guarnieri bodies

27
Q

Inclusion bodies of Rubeola

A

Warthin finkeldey bodies

28
Q

Inclusion bodies of Molluscum contangiosum

A

Henderson-Peterson bodies

29
Q

Dermatome affected in Shingles

A

Thoracic

30
Q

Tzanck smear is an assay used for:

A

HSV and VSV

31
Q

DOC for CMV

A

Ganicyclovir

32
Q

Heterophile positive

Heterophile negative

A

Heterophile positive EBV

Heterophile negative CMV

33
Q

Monospot test or Heterophile antibody test (Paul-Bunnel) is diagnostic of what disease?

A

Infectious mononucleosis

34
Q

What to look for Monospot test?

A

Agglutination of RBCs

35
Q

HHV8 is associated with what conditions?

A

Kaposi sarcoma, AIDS associated B-cell lymphoma, multiple myeloma

36
Q

Primary method for detection of HHV8

A

PCR amplication

37
Q

Enzyme used for PCR amplication

A

Taq polymerase (heat stable enzyme)

38
Q

HPV16 and HPV18 associated in CIN mechanism

A

Inactivation of tumor suppressor proteins p53 and p110-Rb by viral protein E6 and E7

39
Q

HPV 1, 2, 4 causes?

A

Plantar warts

40
Q

Exanthematous phase of measles

A

Red maculopapular eruption beginning on forehead (around the hairline), behind the ears, and on upper neck spreading downwards to the torso and extremities

41
Q

Most common complication of measles

A

Otitis media

Hi-Yield for PLE (6 decks)

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