Virology

Question 1

Typical size range of a virus

Answer 1

20 - 300 nm

Question 2

Protein coat of all viruses

Answer 2

Capsid

*composed of repeating capsomeres

Question 3

Nucleic acid genome + capsid = ?

Answer 3

Neucleocapsid

Question 4

ALL helical viruses are enveloped, TRUE or FALSE?

Answer 4

TRUE

Question 5

Virus that acquires its envelope from nuclear membrane (as o

Answer 5

Herpesviridae

Question 6

Naked RNA viruses

Answer 6

Calicivirus, Picornavirus, Reovirus

Question 7

Naked DNA viruses

Answer 7

Parvovirus, Adenovirus, Papillomavirus, Polyomavirus

Question 8

Infectious particles composed entirely of proteins which are highly resistant to inactivation

Answer 8

Prions

Question 9

All viruses are HAPLOID except ?

Answer 9

Retrovirus which is DIPLOID

Question 10

Viruses with segmented genomes

Answer 10

Bunyavirus, Orthomyxovirus, Arenavirus, Reovirus

*BOAR

Question 11

Negative stranded RNA viruses

Answer 11

Arenavirus, Bunyavirus, Paramyxovirus, Orthomyxovirus, Filovirus, Rhabdovirus

Question 12

How many Phases are involved in a viral growth curve?

Answer 12

6

Phases 0 to 5

Question 13

Phase in growth curve where no virus is detectable inside the cell

Answer 13

Phase 2 - Eclipse Phase

Question 14

Phase in growth curve where a single virus particle infects the cell

Answer 14

Phase 0 - Entry

Question 15

Phase in growth curve where there is a dramatic increase in amount of detectable virus

Answer 15

Phase 3 - Rise Period

Question 16

Phase in growth curve where there is marked derangement of cell function leading to lysis and cell death

Answer 16

Phase 5 - Cytopathic Effect

Question 17

Phase in growth curve where there is decrease in number but continuous function of both cell and virus

Answer 17

Phase 1 - Decline

Question 18

Phase in growth curve where there is a detectable amount of virus which reaches a plateau

Answer 18

Phase 4 - Latent Period

Question 19

Presence of IgM can mean _____ infection

Answer 19

Current/Acute

Question 20

Live Attenuated Vaccines

Answer 20

Yellow Fever
Chicken Pox (VZV)
Sabin’s polio
MMR

Question 21

Only live attenuated vaccine that may be given to HIV positive patients

Answer 21

MMR

Question 22

Killed vaccines

Answer 22

Rabies
Influenza
Polio (Salk’s)
Hepatitis A

Question 23

DNA viruses

Answer 23

Hepadna
Herpes
Adeno
Pox
Parvo
Polyoma
Papilloma

Question 24

ALL DNA viruses have double stranded DNA except?

Answer 24

Parvovirus

Question 25

ALL DNA viruses have linear DNA except?

Answer 25

Papillomavirus
Polyomavirus
Hepadnavirus

Question 26

ALL DNA viruses are icosahedral except?

Answer 26

Poxvirus

Question 27

ALL DNA viruses replicate in the nucleus except?

Answer 27

Poxvirus

*replicates in the cytoplasm

Question 28

Mode of transmission of Parvovirus B19

Answer 28

Respiratory

Transplacental

Question 29

Mode of transmission of Adenovirus

Answer 29

Respiratory

Fecal - Oral

Question 30

Mode of transmission of HPV

Answer 30

Sexual 
Skin contact (break in barrier)

Question 31

Virus associated with slapped cheeks, fever, coryza, sore throat with transient but severe aplastic anemia

Answer 31

Parvovirus B19

Fifth Disease

Question 32

Only virus with fibers, with disease spectrum ranging from URTI to GIT and hemorrhagic cystitis

Answer 32

Adenovirus