VIROLOGY Flashcards

1
Q

Live attenuated vaccines

A
Smallpox
yellow fever
VZV
Sabin polio virus
MMR
Influenza (intranasal)
Note: dangerous to give to IC pts.  Exception - MMR can be given to HIV positive that do not show signs of IC.
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2
Q

Killed vaccines

A

Rabies
Influenza (injected)
Salk Polio
HAV

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3
Q

Recombinant

A

HBV

HPV 6,11,16, and 18

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4
Q

DNA viral genomes

A

All DNA viruses except the Parvoviridae are dsDNA

All are linear except papilloma, poloma, and hepadnaviruses (circular). Parvoridae is ssDNA

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5
Q

RNA viral genomes

A

All RNA viruses except Reovirdae are ssRNA

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6
Q

Herpesvirus

A

DNA virus: DS and linear
envelope: yes
HSV1 and HSV2, VZV, EBV, CMV, HHV-6 (roseola), HHV-8 (Kaposi)

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7
Q

Hepadnavirus

A

DNA virus: DS and partial circular
Envelope: yes
HBV

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8
Q

Adenovirus

A

DNA virus: DS and linear
Envelope: NO
Can cause conjunctivitis

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9
Q

Parvovirus

A

DNA virus: SS and linear
Envelope: no
B19: aplastic crisis in sickle cell disease. slapped cheek disease

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10
Q

Papillomavirus

A

DNA virus: DS and circular
No envelope
HPV

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11
Q

Polyomavirus

A

DNA virus: DS and circular
No envelope
JC virus - progressive multifocal leukoencephalopathy in HIV
BK virus - targets kidney in transplant pts
Junky cerebrum and bad kidney

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12
Q

Poxvirus

A

DNA virus: DS and linear
Yes envelope
Smallpox and Molluscum contagiosum

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13
Q

ID HSV?

A

Tzanck test - detect multinucleated giant cells

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14
Q

Reovirus

A

NO Env.
DS linear RNA
Rotavirus: number one cause of fatal diarrhea in kids

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15
Q

Picornavirus

A
NO Env.  
SS linear RNA
PERCH
Poliovirus Rhinovirus - common cold
Echovirus  Coxsackievirus  HAV
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16
Q

Hepevirus

A

No env.
SS linear RNA
HEV

17
Q

Calicivirus

A

No env.
SS linear RNA
Norovirus - viral gastroenteritus

18
Q

Flavivirus

A

Yes Env.
SS linear RNA
HCV, yellow fever, Dengue, St Louis encephalitis, and West Nile virus

19
Q

Togavirus

A

yes env
SS linear RNA
Rubella, E and W equine encephalitis

20
Q

Retrovirus

A

yes env
SS linear RNA
have reverse transcriptase. HIV and HTLV

21
Q

Coronavirus

A

yes env
SS linear RNA
Coronavirus - common cold and SARS

22
Q

Orthomyxovirus

A

yes env
SS linear RNA
Influenza

23
Q

paramyxovirus

A
yes env
SS linear RNA
Parainfluenzae - croup
RSV - ribavirin
Measles, Mumps
24
Q

rhabdovirus

A

yes env
SS linear RNA
rabies

25
Q

Filovirus

A

yes env
SS linear RNA
Ebola and marburg