VIROLOGY Flashcards
Live attenuated vaccines
Smallpox yellow fever VZV Sabin polio virus MMR Influenza (intranasal) Note: dangerous to give to IC pts. Exception - MMR can be given to HIV positive that do not show signs of IC.
Killed vaccines
Rabies
Influenza (injected)
Salk Polio
HAV
Recombinant
HBV
HPV 6,11,16, and 18
DNA viral genomes
All DNA viruses except the Parvoviridae are dsDNA
All are linear except papilloma, poloma, and hepadnaviruses (circular). Parvoridae is ssDNA
RNA viral genomes
All RNA viruses except Reovirdae are ssRNA
Herpesvirus
DNA virus: DS and linear
envelope: yes
HSV1 and HSV2, VZV, EBV, CMV, HHV-6 (roseola), HHV-8 (Kaposi)
Hepadnavirus
DNA virus: DS and partial circular
Envelope: yes
HBV
Adenovirus
DNA virus: DS and linear
Envelope: NO
Can cause conjunctivitis
Parvovirus
DNA virus: SS and linear
Envelope: no
B19: aplastic crisis in sickle cell disease. slapped cheek disease
Papillomavirus
DNA virus: DS and circular
No envelope
HPV
Polyomavirus
DNA virus: DS and circular
No envelope
JC virus - progressive multifocal leukoencephalopathy in HIV
BK virus - targets kidney in transplant pts
Junky cerebrum and bad kidney
Poxvirus
DNA virus: DS and linear
Yes envelope
Smallpox and Molluscum contagiosum
ID HSV?
Tzanck test - detect multinucleated giant cells
Reovirus
NO Env.
DS linear RNA
Rotavirus: number one cause of fatal diarrhea in kids
Picornavirus
NO Env. SS linear RNA PERCH Poliovirus Rhinovirus - common cold Echovirus Coxsackievirus HAV