virology 17

Question 1

All DNA viruses replicate in the nucleus of the cell except
A. Influenza Virus
B. Herpesvirus 8
C. Variola virus
D. Herpes simplex type1
E. B19

Answer 1

Variola virus

Question 2

The 27-year-old pregnant mother of a child diagnosed with erythema infectiosum is concerned for the health of her fetus. What would be the most likely outcome of fetal infection with the virus causing her child’s disease?
(A) Hydrocephalus
(B) Hydrops fetalis
(C) Mental retardation
(D) Microcephaly
(E) Patent ductus arteriosus

Answer 2

Hydrops Fetails

Question 3

What is the treatment for the cytomegalovirus symptomatic infection?
a. Ketokonazole
b. No treatment is required
c. Gancyclovir
d. Acyclovir
e. Silver Nitrate

Answer 3

Gancyclovir

Question 4

What is the most common cause of congenital mental retardation in U.S?
a. Herpesvirus type 2
b. Heterophil-positive mononucleosis
C. Adeenovirus 44
d. Cytomegalic inclusion disease

Answer 4

Cytomegalic inclusion disease

Question 5

Adenoviruses can be used for…
a. development of the molecular diagnostic tools
b. Vaccine production
c. Treatment of bacterial infections
d. Food production

Answer 5

Vaccine production

Question 6

Which of the following is associated with the blueberry muffin appearance?
a. Varicella-zoster virus
b. Herpesvirus type 1
c. Cytomegalovirus
d. Poxvirus

Answer 6

Cytomegalovirus

Question 7

Which of the following viral family member has a segmented, double-stranded RNA genome and a double-shelled capsid causing gastroenteritis?
a. Coronavindae
b. caliciviridae
c. Reoviridae
d. Adenoviridae
e. Astrovirida

Answer 7

Reoviridae

Question 8

A 55-year-old male develops a rash along the T6 dermatome on the right side of his body. His has a history of immunosuppressive drug therapy for a transplantation, surgery. Which virus is the most likely etiologic agent of this man’s condition?
A. Measles virus
B. Molluscum contagiosum virus
C. Rubella virus
D. varicella-zoster virus
E. Herpes simplex virus

Answer 8

varicella-zoster virus

Question 9

Which of the following cells can be infected with B19?
A. Hepatocytes
B. erythroid cells
C. adipocytes
D. skin cells
E. lymphocytes

Answer 9

erythroid cells

Question 10

The 27-year-old pregnant mother of a child diagnosed with erythema infectiosum is concerned for the health of her fetus. What would be the most likely outcome of fetal infection with the virus causing her child’s disease?
A. Hydrocephalus
B. Mental retardation
C. Patent ductus arteriosus
D. Hydrops fetalis
E. Microcephaly

Answer 10

Hydrops fetalis

Question 11

which of the following are the cancer promoting virus ?
A. Norwalk virus
B. 819
C. I HSV type 1
D. Epstein-barr virus
E. Poliovirus

Answer 11

Epstein-barr virus

Question 12

Rotavirus represents :
A. mot common cause of gastroenteritis in children
B. Most common cause of pneumonia
C. mot common cause of diarrhea in children
D. Most common cause of common cold in adults
E. Cancer promoting virus

Answer 12

mot common cause of gastroenteritis in children

Question 13

19-year-old man was on a tour of Italy with other college students. One day he abruptly became ill with nausea and vomiting followed 5 hours later by abdominal cramps and watery diarrhea. No fever was noted. Which of these viruses is the most likely cause of the man’s illness?
A. Reovirus
B. Adenovirus
C. Rotavirus
D. Calicivirus
E. Astrovirus

Answer 13

Calicivirus

Question 14

Which one of the following best describes the replication of human parvovirus B19?
A. Uses blood group antigen P as cellular receptor
B. Stimulates resting cells to proliferate
C. Readily establishes persistent infections
D. I. Production of infectious progeny requires the presence of a helper virus
E. Entire replication cycle occurs in cytoplasm

Answer 14

Uses blood group antigen P as cellular receptor

Question 15

The use of live oral polio vaccine has been replaced by inactivated polio vaccine in many countries. Which of the following is the primary reason?
A. There is a greater risk of vaccine-induced disease than wild virus-induced disease in areas where poliovirus has been eradicated
B. Circulating poliovirus strains have changed and the live vaccine is no longer effective in many countries
C. Non of the above
D. It is more cost effective to use the inactivated vaccine
E. Only a single dose of inactivated vaccine is necessary compared with multiple doses of the oral vaccine.

Answer 15

There is a greater risk of vaccine-induced disease than wild virus-induced disease in areas where poliovirus has been eradicated

Question 16

All DNA viruses replicate in the nucleus of the cell except:
A. Herpesvirus 8
B. B19
C. Influenza virus
D. Herpes simplex type 1
E. Variola virus

Answer 16

Variola virus