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Mycology & Virology > Virology > Flashcards

Virology Flashcards

1
Q

Intracellular organisms unable to reproduce itself outside the host cell

A

virus

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2
Q

All viruses are haploid except for

A

RETROVIRUS

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3
Q

Virus multiplies by binary fission

True or False

A

False

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4
Q

entire infectious unit of virus

A

virion

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5
Q

internal core of virus

A

genome

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6
Q

protein coat that surrounds the genome

A

capsid

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7
Q

Subunits of capsid are called

A

CAPSOMERES

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8
Q

Type of capsomeres

A

icosahedral
helical
complex

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9
Q

Virus without envelope are classified as

A

NAKED

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10
Q

Viruses are resistant to

A

antimicrobial

antibacterial

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11
Q

Viruses can survive long periods at

A

-70degC when freeze dried

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12
Q

Viruses can be killed with ____ but are somewhat resistant to _____

A

moist heat

dry heat

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13
Q

These inactivates viruses

A

UV and XRAY irradiation

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14
Q

Inactivate viruses that have lipid envelope

A

Chloroform

Ether

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15
Q

Protein shell or coat that encloses the nucleic acid genome that is built
of structural units of a virion

A

Capsid

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16
Q

DNA (deoxyribonucleic acid) or RNA (ribonucleus acid)

A

Nucleic Acid

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17
Q

Nucleic acid + Capsid (Enclosed)

A

Nucleocapsid

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18
Q

Morphological units seen on the surface of particles and represent
clusters of structure units or polypeptide

A

Capsomeres

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19
Q

A lipid containing membrane that surrounds some viral particles.

A

Envelope

20
Q

A lipid containing membrane that surrounds some viral particles.

A

Envelope

21
Q

It is acquired during viral maturation by a budding process through a cell membrane

A

Envelope

22
Q

Envelope viruses has a ______ appearance inside the envelope

A

pleomorphic

23
Q

the smallest functional unit equivalent to building units of the capsid. Basic protein that acts as building blocks of the coat

A

Structural units- Protomers

24
Q

Lysis is required for __________ and not for ___________

A

icosahedral pattern

helical pattern

25
Q

the most efficient arrangement for subunits in a closed shell

A

Cubic symmetry

26
Q

observed with animal viruses is the

A

icosahedral pattern

27
Q

protein subunits are bound in a periodic way to the viral nucleic acid, winding into a helix

A

Helical symmetry

28
Q

mostly used to distinguish different types of RNA viruses

A

Baltimore Classification/Scheme

29
Q

is a proteinaceous infectious material

A

PRION

30
Q

PRION’s structure is composed of

A

insoluble beta pleated sheet

31
Q

PRION affects

A

NS such as fibrils and vacuole (spongy)

32
Q

Normal cellular protein misfolded when a portion of its α-helical coil structure refolds to a β-sheet, producing a mutant protein
May be secreted in the urine

A

Transmissible spongiform encephalopathies (TSE)

33
Q

Animal infection: Scrapie

A

sheep

34
Q

Animal infection: Chronic wasting disease

A

Mule, deer, and elk

35
Q

Animal infection: Transmissible mink encephalopathy

A

Mink

36
Q

a family of progressive neurodegenerative disorders that affect both humans and animals

A

Human infection- Prion diseases

37
Q

Types of prions

A

Sporadic
Genetic
Variant
Iatrogenic

38
Q

What animal affects Bovine spongiform encephalopathy (BSE)

A

Cattle

39
Q

Viral genomes contain information which:

A

ensures replication
packaging
alters structure

40
Q

All are double stranded-DNA except

A

parvovirus

41
Q

All are icosahedral DNA, except

A

Poxvirus(COMPLEX)

42
Q

All are enveloped, Except

A

Papovavirus
Adenovirus
Parvovirus

43
Q

All multiply in nucleus, Except

A

Poxvirus (cytoplasm)

44
Q

Largest DNA virus

A

poxvirus

45
Q

smallest DNA virus

A

Parvovirus

Mycology & Virology (2 decks)

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