Viro Final Tolka Flashcards
Which of the following is false regarding Rhabdoviridae?
a. Visions are very stable in the environment
b. Can withstand alkaline pH
c. Can withstand UV radiation from the sun
d. Detergent based disinfectants and iodine solutions are effective disinfectants against Rhabdoviridae
c. Can withstand UV radiation from the sun
True or False?
Rhabdoviridae replicates in the nucleus of the host cell?
False-cytoplasm
Which of the following genus’ of Rhabdoviridae is responsible for rabies virus?
a. Lyssavirus
b. Vesiculovirus
c. Ephemerovirus
d. Novirhabdovirus
a. Lyssavirus
Which of the following is not a reservoir for rabies virus in north america?
a. Skunks
b. Raccoons
c. Foxes
d. White tailed deer
e. Wolves
d. White tailed deer
In central and south america, rabies virus is transmitted to cattle by?
a. Bobcat
b. Vampire bats
c. Prairie dog
d. Grey wolf
b. Vampire bats
To which family does the rabies virus belong to?
a. Noroviridae
b. Retroviridae
c. Vesiculoviridae
d. Rhabdoviridae
d. Rhabdoviridae
What is the current status of rabies or rabies-like viruses risk level in North America?
a. No risk
b. Low risk
c. Medium risk
d. High risk
b. Low risk
The Ephemeralvirus genus has an important member that causes disease in?
a. Pigeons
b. Cattle
c. Pigs
d. Dogs
b. Cattle
Which of the following descriptions of Rhabdoviridae virion properties is accurate?
a. Enveloped, cone shaped, double stranded, circular, negative sense RNA
b. Enveloped, cone shaped, single stranded,linear, positive sense RNA
c. Enveloped, cone shaped, double stranded, linear, negative sense RNA
d. Enveloped, cone shaped, double stranded, linear, negative sense RNA
d. Enveloped, cone shaped, double stranded, linear, negative sense RNA
If you wanted to design a neutralizing antibody-inducing vaccine against rabies virus to prevent its attachment and internalization, which protein of the virus would you target?
a. N protein
b. C protein
c. G protein
d. P protein
c. G protein
If you wanted to design a neutralizing antibody-inducing vaccine against rabies virus to prevent its attachment and internalization, which protein of the virus would you target?
a. N protein
b. C protein
c. G protein
d. P protein
c. G protein
Which rhabdovirus protein facilitates budding from an infected cell?
a. M protein
b. C protein
c. G protein
d. P protein
a. M protein
Which of the following disinfectants would you use to eliminate the rhabdovirus from your examination table in the clinic?
a. Oxidizing agents
b. Detergent based disinfectants
c. Iodine based disinfectants
d. All of the above
d. All of the above
Where in the cell do rhabdoviruses replicate?
a. Endoplasmic reticulum
b. Nuclear por
c. Cytoplasm
d. Nucleus
c. Cytoplasm
True or False?
The G, N, P, M, and L mRNAs of rhabdoviruses are all translated by free cytoplasmic ribosomes?
False
A healthy looking dog is brought to you on grounds that it bit somebody an hour ago. The owner provides records of vaccination against rabies. Would you quarantine the dog for observation? If so how long?
a. The dog should be quarantined for at least two weeks
b. The dog should not be quarantined, but ask the owner to report for examination everyday for two weeks
c. The dog should be quarantined for at least 10 days
d. No quarantine is necessary because the dog has been vaccinated against rabies
c. The dog should be quarantined for at least 10 days
Which of the following is a phase in clinical rabies?
a. Paralytic phase
b. Fury phase
c. Prodromal phase
d. All of the above
d. All of the above
At what phase of clinical rabies would you observe photophobia and the resulting excessive salivation?
a. Paralytic phase
b. Fury phase
c. Prodromal phase
d. All of the above
a. Paralytic phase
Fury in rabid dogs is associated with virus extensively replicating in the?
a. Muscles
b. Spinal cord
c. Salivary glands
d. Limbic system of the nervous system
d. Limbic system of the nervous system
True or False?
If histopathology results reveal the presence of Negri bodies in the hypothalamus of an animal suspected of rabies, it is enough to confirm rabies virus infection?
True
A small farmer has two horses, 6 cows and 15 pigs. He reports three sick animals (a cow, a horse and 5 pigs). You recognize oral vesicles in the cow and the horse, and coronary band vesicles in the pigs. From choices given below, what disease should come to your mind first before you consider other differentials?
a. Rinderpest
b. A small farmer has 2 horses, 6 cows and 15 pigs. He has vesicular disease of swine
c. Vesicular stomatitis
d. Foot and mouth disease
c. Vesicular stomatitis
A horse is presented with vesicular lesions shown in the photomicrograph below. What is your initial clinical diagnosis and why?
a. Excluding thermal burns, it is vesicular stomatitis, because it is the only vesicular disease in horses
b. Vesicular exanthema of horses, because the equine coital exanthema virus causes such lesions
c. Foot and mouth disease, because horses are highly susceptible to FMDV
d. Swine vesicular disease, because horses can be infected with SVDV
a. Excluding thermal burns, it is vesicular stomatitis, because it is the only vesicular disease in horses
How can you distinguish lesions caused by vesicular stomatitis virus in cattle from those caused by FMDV?
a. Vesicular stomatitis virus does not cause lesions on the tongue in cattle
b. Lesions in both cases are indistinguishable
c. Lesions caused by FMDV are smaller compared to those caused by vesicular stomatitis virus
d. Lesions caused by FMDV are larger compared to those caused by vesicular stomatitis virus
b. Lesions in both cases are indistinguishable
SVD is a vesicular disease that has not been reported in North America. What other vesicular diseases of cattle, swine or horses do you know?
a. Vesicular stomatitis
b. Foot and mouth disease
c. Vesicular exanthema of swine
d. All of the above
d. All of the above
