Viro exam 2 Flashcards
Polymerase Chain Reaction (PCR) is used to?
a. Stain the virus and make it visible
b. Detect any viral proteins
c. Amplify the viral DNA
d. Detect antibodies
c. Amplify the viral DNA
Which is not a step of PCR?
a. Annealing
b. Processing
c. Extension
d. Denaturing
b. Processing
True or False?
Metagenomics is used to detect specific pathogens in a sample?
False- used for random detection
Which diagnostic test allows hundreds of pathogens to be screened at the same time using one chip?
a. PCR
b. Metagenomics
c. Microarrays
d. ELISA
c. Microarrays
Acyclovir is used for the treatment of?
a. Herpesviruses
b. HIV
c. Poxviruses
d. Flu viruses
a. Herpesviruses
Which is not true about Acyclovir?
a. Administered as a prodrug
b. Synthetic form of Guanosine
c. Prevents elongation of NA sequence
d. Toxic to the host cell
d. Toxic to the host cell
Amantadine is used to treat the flu virus and works on the ____?
a. M1 channel
b. M2 channel
c. P53
d. Rb
b. M2 channel
Which pair is incorrect?
a. Oseltamivir—> influenza A & B
b. Zidovudine(ZVD)/ Azidothymidine (AZT)—> thymine copycat
c. Zidovudine(ZVD)/ Azidothymidine (AZT)—> Nucleoside Analog reverse transcriptase inhibitors k
d. Protease inhibitors—> HIV
e. All are correct
e. All are correct
Which is not a form of a “live-attenuated” vaccine?
a. Attenuation of viruses by serial passage in cultured cells
b. Attenuation of viruses by serial passage in heterologous hosts
c. Attenuation by selection of cold-adapted mutants/reassortments
d. Using inactivated/non-replicating viruses as vaccines
d. Using inactivated/non-replicating viruses as vaccines
What type of vaccine would you use if you wanted to later test to see who was vaccinated or naturally infected?
a. Live attenuated
b. DIVA
c. Inactivated vaccines
d. Vaccines made from only viral proteins
b. DIVA
True or False
Sterilization destroys/eliminates all forms of microbial life/pathogens
True
Which type of Poxviruses are ovoid and resemble a ball of yarn?
a. Parapoxviruses
b. Orthopoxviruses
c. Suipoxviruses
d. None of the above
a. Parapoxviruses
True or False?
Only the extracellular enveloped visions of poxviruses are infectious
False. both EEV and IMV forms are infectious
What is the correct order of the Poxvirus “Symphony”?
a. Ma-pu-pa-ve-sca
b. Pu-ma-ve-sca
c. Ma-pa-ve-pu-sca
c. Ma-pa-ve-pu-sca
Which is false?
a. Poxviruses are resistant to detergents/disinfectants(low lipid)
b. Poxviruses replicate in the cytoplasm
c. Main species of concern in Cowpox are cows
d. Sheep show a systemic form of the disease in sheep
c. Main species of concern in Cowpox are cows
Which poxvirus shows a classical “horseshoe” shaped area of scabs?
a. Suipoxvirus
b. Cowpox
c. Capripox
d. Pseudocowpox
d. Pseudocowpox
True or False?
Both sheep pox and goat pox are reportable?
True
Which form of fowlpox is considered the most severe?
a. Cutaneous(dry)
b. Diphtheric(wet)
c. Ocular
d. All equally severe
b. Diphtheric(wet)
Which poxvirus will you see Bollinger and barrel bodies?
a. Cowpox
b. Suipox
c. Fowlpox
d. Capripox
c. Fowlpox
True or false?
Circoviruses can replicate in any cell
False. can only replicate in an actively dividing cell
Which virus causes PMWS in piglets?
a. Porcine circovirus 1
b. Porcine circovirus 2
c. Porcine circovirus 3
d. All porcine circoviruses
b. Porcine circovirus 2
What type of inclusion bodies are seen in circovirus infections?
a. Bollinger bodies
b. Borrel bodies
c. Cowdry Bodies
d. Botyroid Bodies
d. Botyroid Bodies
Porcine dermatitis and nephropathy syndrome is caused by?
a. Porcine circovirus 1
b. Porcine circovirus 2
c. Porcine Herpesvirus 1
d. Porcine Herpesvirus 2
b. Porcine circovirus 2
What genus is the chicken anemia virus in?
a. Gyrovirus
b. Circovirus
a. Gyrovirus
What are the clinical signs of chicken infectious anemia? (2 answers)
a. Diarrhea
b. Aplastic anemia
c. Immunosuppression
d. Autoimmnue
b. Aplastic anemia
c. Immunosuppression
Which is false?
a. Herpesviruses don’t survive well in the environment
b. Herpesviruses replicated in the nucleus
c. All have persistent infections and can from Synctia
d. Have Botyroid bodies
d. Have Botyroid bodies
True or False?
Alphaherpesvirinae members have the longest replication cycle
False. they have a short replication cycle and are the fastest
Which subtype is the “genital” type in bovine herpesvirus 1 infections?
a. 1.1
b. 1.2
c. 1.3
d. 1.4
b. 1.2
Bovine herpesvirus 1 goes latent in which two nerves?
a. Sciatic
b. Facial
c. Trigeminal
d. Cephalic
a. Sciatic
c. Trigeminal
True or False?
The respiratory form (1.1) of Bovine herpesvirus 1 causes infectious Bovine Rhinotracheitis
True
How can you differentiate the ocular form of BHV-1 from true “pink eye”?
a. BHV-1 is only in the aqueous humor
b. Pink eye is caused by BHV-1
c. BHV-1 is confined to the conjunctiva
d. BHV-1 spreads to the keratoconjunctiva
c. BHV-1 is confined to the conjunctiva
Which BHV-1 vaccine can cause abortion in pregnant cows?
a. Parental Vaccine
b. Intranasal vaccine
c. Both
d. Neither
a. Parental Vaccine
Bovine Ulcerative Mammillitis is caused by?
a. BHV-1 (sometimes 4)
b. BHV-2( sometimes 4)
c. Only BHV-2
d. Only BHV-4
b. BHV-2( sometimes 4)
True or False?
Porcine herpesvirus 1 causes “mad itch” in Pigs?
False. pigs rarely itch with these infections but mad itch is seen in the other hosts.
Which strain is the most virulent?
a. Equine herpesvirus 4
b. Equine herpesvirus 1
c. Equine herpesvirus 2
d. Equine herpesvirus 5
b. Equine herpesvirus 1
Which is not a characteristic of EHV-1 infections?
a. Abortion storms every 3 years
b. Encephalomyelopathy
c. Cutaneous warts
d. Respiratory disease
c. Cutaneous warts
Canine herpesvirus 1 infections are most serious in?
a. Prenatal/Neonatal puppies
b. Adult dogs
a. Prenatal/Neonatal puppies
Which is an important factor in CHV-1 infections?
a. Confections with other pathogens
b. Body temperature of puppies
c. Breed
d. Number of puppies in litter
b. Body temperature of puppies
Feline herpesvirus 1 causes?
a. Infectous feline rhinotracheitis
b. Abortions (not directly due to the virus though)
c. Corneal edema
d. All of the above
d. All of the above
True or False?
Gallid herpesvirus 1 causes infectious laryngotracheitis?
True
Which is false regarding galled herpesvirus 1?
a. Pump handle respiration
b. Latency in trigeminal nerve
c. Forms diphtheric membranes
d. Severe epizootic form most common
d. Severe epizootic form most common
True or False?
B19 chickens are resistant to Marecks disease?
False. B21 are resistant
Porcine herpesvirus 2 causes? (2 answers)
a. Inclusion body rhinitis
b. Mareks disease
c. Malignant catarrhal fever
d. Reproductive issues
a. Inclusion body rhinitis
d. Reproductive issues
Zebra striping is seen in?
a. Alphaherpesvirinae
b. Betaherpesvirinae
c. Gammaherpesvirinae
d. Deltaherpesvirinae
c. Gammaherpesvirinae
What is the biological vector for African swine fever?
a. Hard ticks
b. Soft ticks
c. Cullicoides
d. Lice
b. Soft ticks
True or False?
Blackberry jam spleen is seen in african swine fever infections?
True
What treatment should you start if you suspect a case of african swine fever?
a. Antibiotics
b. Supportive therapy until authorities arrive
c. Just leave
d. Report to authorities but don’t attempt treatment
d. Report to authorities but don’t attempt treatment
Feline panluekopenia is caused by?
a. Canine parvovirus 1
b. Feline parvovirus
c. Feline herpesvirus
d. Any parvovirus infection
b. Feline parvovirus
Which two virulent strains are mostly seen in America?
a. Canine parvovirus 1
b. Canine parvovirus 2a
c. Canine parvovirus 2b
d. Canine parvovirus 2c
c. Canine parvovirus 2b
d. Canine parvovirus 2c
True or False?
Porcine parvovirus mainly manifests as diarrhea and GI disease?
False. SMEDI
True or False?
Abortions are a common feature of porcine parvovirus infections?
False. stillbirth embryonic death, mummification and fertility are common but abortion is not
Which is false in regards to papillomaviruses?
a. E6–>p53
b. E7–>Rb
c. Fibropapilloma–> Bovine types 1,2,5
d. Sarcoids–> Equine type 2
d. Sarcoids–> Equine type 2
Which combination is associated with alimentary carcinomas in bovine species?
a. Bracken fern and BPV-2
b. Bracken fern and BPV-4
c. Bracken fern and any BVP strain
d. Bracken fern and BVP-1
b. Bracken fern and BPV-4
Which horse breed is resistant to sarcoids?
a. Arabian
b. Appaloosa
c. Standardbred
d. American quarter horse
c. Standardbred
Which adenovirus genus contains bifurcated penton fibers?
a. Mastadenovirus
b. Aviadenovirus
b. Aviadenovirus
How was infectious canine hepatitis distinguished from the viruses?
a. Ferrets were susceptible to ICH but resistant to kennel cough
b. Ferrets were resistant to ICH but susceptible to kennel cough
c. Ferrets were resistant to ICH but susceptible to Canine distemper
d. Ferrets were susceptible to ICH but resistant to canine distemper
c. Ferrets were resistant to ICH but susceptible to Canine distemper
Which vaccine can actually pose a risk for development of corneal edema?
a. CAV-1 vaccine
b. CAV-2 vaccine
c. Both
d. Neither
a. CAV-1 vaccine
True or False?
Canine adenovirus 2 causses kennel cough?
True
Which strain causes severe respiratory disease in SCID foals?
a. EAV-3
b. EAV-2
c. EAV-1
d. All equine adenovirus strains cause these issues
c. EAV-1