Viral skin infections

Question 1

Prodrum 1-12 days post infection
High fever
Coryza, cough, conjunctivitis (3 c’s)
Koplik;s spots

Answer 1

Rubeola

Question 2

Measles complications

Answer 2

Pneumonia (kills most)
Diarrhea
CNS - enceph, SSPE

Question 3

Multinucleated giant cells

Answer 3

Measles

Question 4

Mild exanthematous disease the resembles measles
Children often escape this infection
Very bad for fetus - esp in 1st trimester

Answer 4

Rubella

Can cause congenital rubella syndrome (cariac defects, eyeball defects, hearing loss)

Question 5

2 unique properties of herpes simplex virus:

Answer 5

1. Capacity to invade and replicate in CNS

2. Ability to establish latent infections

Question 6

Shallow vesicles on erythematous base
Ballooning pathology, vesicles crust over painfully
Enlarged fused cells on Tzanck smear

Answer 6

HSV

Question 7

Retrograde transport of virus thru sensory neurons and ultimate infection of the DORSAL ROOT GANGLIA (virus remains latent).

Answer 7

HSV

Question 8

Virus that infects thru conjunctiva or resp tract mucosa
Replicates in regional lymph nodes, primary viremia 4-6 days after infxn
Replicates in liver and spleen to generate secondary viremia that coincides with rash 10-14 days after infection

Answer 8

Chicken pox
(Varicella zoster virus)

• Pt most contagious 1-2 days before rash and 4-5 days after
• Prodrome in older kids and adults

Question 9

Sequence of fever followed by rose colored rash

-Fever 2-5 days

Answer 9

Roseola Infantum

human herpes virus 6 or 6th disease

Question 10

Prodromal illness of several days w/ mild sx

Then slapped cheek rash

Answer 10

Parvovirus B19

Fifth Disease, erythema infectiosum

Question 11

HPV 6 and 11

Answer 11

ano-genital warts

Question 12

HPV 16 and 18

Answer 12

Cervical dysplasia